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substantial decrease » substantially increased (Expand Search)
significant role » significant genes (Expand Search), significant _ (Expand Search), significant bit (Expand Search)
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The potential role of vitamin D supplementation as a gut microbiota modifier in healthy individuals
Published 2020“…Comparing supplementation responders and non-responders we found more pronounced changes in abundance of major phyla in responders, and a significant decrease in Bacteroides acidifaciens in non-responders. …”
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Pharmacist Role in Hypertension Management in the Community Setting: Questionnaire Development, Validation, and Application
Published 2023“…Pharmacists can play a substantial role in decreasing the burden of the disease. …”
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Dexamethasone and transdehydroandrosterone significantly reduce pulmonary epithelial cell injuries associated with mechanical ventilation.
Published 2021“…Bubble flows caused significant cell injury. Preexposure to DEX or DHEA decreased cell death significantly. …”
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apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes.
Published 2021“…Apoproteins apoA2, apoC1, apoC3 and apoE are decreased in women with GDM and may have a role in inflammation, as apoA2 and C3 correlated with CRP. …”
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Wind energy potential along the onshore and offshore Qatar
Published 2020“…The utilization of non-conventional energies over the conventional sources helps to reduce the carbon emissions significantly. The present study aims at investigating the wind energy potential at select coastal locations of Qatar using ERA5 winds. …”
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Role of organic cation in modern lead-based perovskites
Published 2019“…Hybrid organic-inorganic metal perovskites (ABX3, A- organic cation, B-metal ion, X-halide ion) have shown significant potential as thin-film solar cells or Dye solar cells (DSC) materials. …”
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Selection of Bacillus spp. with decontamination potential on multiple Fusarium mycotoxins
Published 2021“…B. megaterium BM344-1, having significant biodegrading properties on multiple Fusarium mycotoxins, can be considered for its potential application as a mycotoxin decontamination agent in the food industry.…”
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Cutaneous Aβ-Non-nociceptive, but Not C-Nociceptive, Dorsal Root Ganglion Neurons Exhibit Spontaneous Activity in the Streptozotocin Rat Model of Painful Diabetic Neuropathy .
Published 2020“…Compared with control, we found in STZ-rats with established pain hypersensitivity (5 weeks post-STZ) several significant changes including: (a) A 23% increase in the incidence of spontaneous activity (SA) in Aβ-LTMs (but not C-mechanosensitive nociceptors) that may cause dysesthesias/paresthesia suffered by DPNP patients, (b) membrane hyperpolarization and a ∼85% reduction in SA rate in Aβ-LTMs by K7 channel activation with retigabine (6 mg/kg, i.v.) suggesting that K7/M channels may be involved in mechanisms of SA generation in Aβ-LTMs, (c) decreases in AP duration and in duration and amplitude of afterhyperpolarization (AHP) in C-and/or Aβ-nociceptors. …”
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Phenolic contents-based assessment of therapeutic potential of Syzygium cumini leaves extract
Published 2019“…Syzygium cumini (S. cumini) is an evergreen tropical plant that is well recognized for its therapeutic potential of common diseases. In this study, the therapeutic potential and biomedical application of S. cumini are assessed in vitro and in vivo to find its effectiveness for different complications. …”
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Synthesis and Pharmacological Evaluation of Different Piperine Analogs for Therapeutic Potential to Prevent ER Stress
Published 2015“…Our findings indicate that exposure to tunicamycin (0.5 µg/mL) for 2 hours induces the expression of GRP78 and CHOP, and causes a significant reduction in renal cell viability. Pre-treatment of cells with piperine and its cyclohexylamino analog decreased the tunicamycin-induced upregulation of GRP78 and CHOP. …”
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Low electro-synthesis potentials improve permselectivity of polymerized natural phenols in biosensor applications
Published 2017“…Permselective properties of natural phenols were significantly improved at low polymerization potentials. …”
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Silymarin-albumin nanoplex: Preparation and its potential application as an antioxidant in nervous system in vitro and in vivo
Published 2019“…In LPS-treated cells, pretreatments with silymarin-HSA noncomplex recovered the cell viability and decreased the ROS level and corresponding apoptosis more significantly than free silymarin. …”
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Ziziphus nummularia attenuates the malignant phenotype of human pancreatic cancer cells: Role of ros
Published 2021“…Pretreatment with N-acetylcysteine, an ROS scavenger, attenuated the anti-proliferative effect of ZNE. In addition, ZNE significantly decreased the migratory and invasive capacity of Capan-2 with a concomitant downregulation of integrin α2 and increased cell–cell aggregation. …”
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Host genetic variants potentially associated with SARS-CoV-2: A multi-population analysis
Published 2020“…Conclusion: Multiple genetic variants, which could potentially modulate SARS-CoV-2 infection, are significantly variable between populations, with the lowest frequency observed among Africans. …”
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Host Genetic Variants Potentially Associated With SARS-CoV-2: A Multi-Population Analysis.
Published 2020“…Multiple genetic variants, which could potentially modulate SARS-CoV-2 infection, are significantly variable between populations, with the lowest frequency observed among Africans. …”
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SIRT1 may play a crucial role in overload-induced hypertrophy of skeletal muscle
Published 2017“…These findings, along with the well-known regulatory roles that SIRT1 plays in modulating both anabolic and catabolic pathways, allow us to propose the hypothesis that SIRT1 may actually play a crucial causal role in overload-induced hypertrophy of skeletal muscle. …”
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