Search alternatives:
side » size (Expand Search), wide (Expand Search), site (Expand Search)
decrease » increase (Expand Search)
side » size (Expand Search), wide (Expand Search), site (Expand Search)
decrease » increase (Expand Search)
-
1
Detection of statistically significant network changes in complex biological networks
Published 2017“…<h3>Background</h3><p dir="ltr">Biological networks contribute effectively to unveil the complex structure of molecular interactions and to discover driver genes especially in cancer context. …”
-
2
Integrating Genome Sequencing and Untargeted Metabolomics in Monozygotic Twins with a Rare Complex Neurological Disorder
Published 2024“…<p dir="ltr">Multi-omics approaches, which integrate genomics, transcriptomics, proteomics, and metabolomics, have emerged as powerful tools in the diagnosis of rare diseases. We used untargeted metabolomics and whole-genome sequencing (WGS) to gain a more comprehensive understanding of a rare disease with a complex presentation affecting female twins from a consanguineous family. …”
-
3
Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration
Published 2018“…<h3>Background</h3><p dir="ltr">Converging evidence suggests a role for microglia-mediated neuroinflammation in Parkinson’s disease (PD). Animal models of PD can serve as a platform to investigate the role of neuroinflammation in degeneration in PD. …”
-
4
-
5
-
6
-
7
Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
Published 2025“…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…”
-
8
Patients with early onset of type 1 diabetes have significantly higher GG genotype at position 49 of the CTLA4 gene
Published 2004“…Type 1 diabetes (T1D) is a complex autoimmune disease. Several genetic loci have been implicated in the susceptibility to this illness. …”
Get full text
Get full text
Get full text
article -
9
Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis
Published 2019“…Specifically, symptom queries were first determined to be significantly predictive of subsequent 12-step queries if the probability of querying a medical symptom by those who later sought information about the 12-step program exceeded the probability of that same query being made by a comparison group of all other Bing users in the United States. …”
-
10
Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …”
-
11
Qatar Health 2023: Showcasing how we emerged from navigating two storms
Published 2023“…The 2023 conference theme was “Clinical and Public Health Advances and Updates in Managing Complex Diseases”. The last few years have been extremely intense for everyone around the world, whether we consider the general population or healthcare professionals and support staff, dealing with and recovering from the COVID-19 pandemic. …”
-
12
-
13
Epigenetic DNA Methylation Signatures Associated With the Severity of Paget’s Disease of Bone
Published 2022“…Additionally, methylation profiles in 11 regions showed Bonferroni-significant association with disease severity including six islands (located in VCL, TBX5, CASZ1, ULBP2, NUDT15 and SQSTM1), two gene bodies (CXCR6 and DENND1A), and 3 promoter regions (RPL27, LINC00301 and VPS29). …”
-
14
Sestrin2 as a Novel Biomarker and Therapeutic Target for Various Diseases
Published 2017“…Thus, the aim of this review is to discuss the upstream regulators and the downstream effectors of Sestrins and to highlight the significance of Sestrin2 as a biomarker and a therapeutic target in diseases such as metabolic disorders, cardiovascular and neurodegenerative diseases, and cancer.…”
-
15
The Use of Modified Composite Zeolite as A Novel Approach to Dental Hygiene Formulation
Published 2024Get full text
doctoralThesis -
16
Exome sequence analysis of rare frequency variants in Late-Onset Alzheimer Disease
Published 2023“…<p dir="ltr">Alzheimer disease (AD) is a leading cause of dementia in elderly patients who continue to live between 3 and 11 years of diagnosis. …”
-
17
Gut Microbiota in Familial Mediterranean Fever: Insights into Microbial Patterns and Disease Severity
Published 2025“…Our findings revealed no significant differences in gut microbiota composition or diversity between FMF patients and healthy controls, nor among FMF subgroups stratified by disease severity. …”
Get full text
Get full text
Get full text
masterThesis -
18
Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”
-
19
Advances in Huntington’s Disease Biomarkers: A 10-Year Bibliometric Analysis and a Comprehensive Review
Published 2025“…Given the complex pathology of HD, biomarkers are essential for performing early diagnosis, monitoring disease progression, and evaluating treatment efficacy. …”
-
20
ALOX5AP gene variants show differential association with coronary artery disease in different populations
Published 2010“…Coronary artery disease (CAD) is a complex disease with various components, genetic as well as environmental. …”
Get full text
Get full text
Get full text
article