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clinically » clinical (Expand Search), critically (Expand Search)
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Time to diagnose and time to surgery in patients presenting with necrotizing fasciitis: a retrospective analysis
Published 2025“…Demographic data, comorbidities, clinical features, treatment, and outcomes were analyzed. …”
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Current trends and future orientation in diagnosing lung pathologies: A systematic survey
Published 2025“…Lung diseases pose a significant threat to public health worldwide, resulting in a substantial number of fatalities. …”
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A Clinically Interpretable Approach for Early Detection of Autism Using Machine Learning With Explainable AI
Published 2025“…The novelty of this work lies in the integration of explainable AI with robust preprocessing and age-specific modeling across multiple ASD datasets, addressing both diagnostic accuracy and clinical interpretability. It can be considered that the suggested method can efficiently diagnose ASD at a very early stage and enhance the understanding of ASD diagnosis clinically.…”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
Published 2025“…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
Published 2025“…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…”
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The impact of enteric coating of aspirin on aspirin responsiveness in patients with suspected or newly diagnosed ischemic stroke: prospective cohort study: results from the (ECASIS...
Published 2022“…ASA non-responsiveness showed no significant difference between the two formulations (P-ASA vs. …”
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Patient with clinical celiac disease mimicking triple‐negative essential thrombocythemia
Published 2023“…She was initially diagnosed as triple-negative ET based on a bone marrow biopsy. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …”