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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Optimizing register binding in FPGAs using simulated annealing
Published 2017“…This paper proposes a solution that applies simulated annealing after binding variables to storage elements. This solution optimizes the assignment of variables onto registers when standard techniques such as clique partitioning are used; and onto on-chip memory banks when two different memory binding techniques are used. …”
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Enhancing eggplant (Solanum melongena L.) yield and water use efficiency through optimized irrigation and nitrogen practices in open field conditions
Published 2024“…Applying 70 kg N ha−1 during deficit irrigation (I1 + F2) produced the highest fruit yield compared to other treatments, although no significant difference was found with I1 + F1. The study highlights the importance of optimized nitrogen and irrigation management for maximizing eggplant production in water-limited environments.…”
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Optimal design of power system stabilizers using evolutionary programming
Published 2002“…The optimal design of power system stabilizers (PSSs) using evolutionary programming (EP) optimization technique is presented in this paper. …”
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Using genetic algorithms to optimize software quality estimation models
Published 2004“…Hence, the accuracy of the models often deteriorates significantly when they are used to classify new data. …”
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Mathematical Model-Based Optimization of Continuous Flow Photobioreactor Operating at Steady State Using MATLAB Optimization Function
Published 2024“…The <i>fmincon</i> optimization results agree well with the literature that used different optimization methods. …”
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Augmented arithmetic optimization algorithm using opposite-based learning and lévy flight distribution for global optimization and data clustering
Published 2022“…This paper proposes a new data clustering method using the advantages of metaheuristic (MH) optimization algorithms. …”
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Hemodynamics of small aneurysm pairs at the internal carotid artery
Published 2012“…The maximum wall shear stress increases for serial aneurysms, but decreases for parallel aneurysms. Interaction between parallel aneurysms is not significant; however, the proximal aneurysm in serial aneurysms may be subject to a greater rupture risk.…”
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
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Optimizing the Cleaning Frequency of Solar Photovoltaic (PV) systems Using Numerical Analysis
Published 2021Get full text
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Optimal scheduling algorithm for residential building distributed energy source systems using Levy flight and chaos-assisted artificial rabbits optimizer
Published 2023“…The increase in demand for MicroGrids (MGs) is a significant factor in the provision of electricity in the future, mainly due to the use of renewable energy sources, which reduces the release of hazardous gases. …”
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Optimal scheduling algorithm for residential building distributed energy source systems using Levy flight and chaos-assisted artificial rabbits optimizer
Published 2023“…<p>The increase in demand for MicroGrids (MGs) is a significant factor in the provision of electricity in the future, mainly due to the use of renewable energy sources, which reduces the release of hazardous gases. …”
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