Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”

Both decreasing interstructural space size and increasing total cover increase shrimp abundance on artificial structures deployed in a UAE seagrass bed by Bartholomew, Aaron

Get full text

Patients with early onset of type 1 diabetes have significantly higher GG genotype at position 49 of the CTLA4 gene by Zalloua, Pierre

“…The GG genotype was also significantly higher among patients (12.6%) than in controls (4.2%). χ2 analysis and family-based association studies were performed and suggested the association of CTLA4 exon 1 G polymorphism with T1D (p = 0.0229). …”
Get full text
Get full text
Get full text

Assessing uncertainty in image-based monitoring: addressing false positives, false negatives, and base rate bias in structural health evaluation by Vagelis Plevris (14158863)

“…The Base Rate Bias plays a significant role, as low probabilities of actual damage often lead to misinterpretation of positive results. …”

A component analysis of positive behaviour support plans by Grey, Ian

“…Method Sixty-one staff working with individuals with intellectual disability and challenging behaviours completed longitudinal competency-based training in PBS. Each staff participant conducted a functional assessment and developed and implemented a PBS plan for one prioritised individual. …”
Get full text
Get full text
Get full text
Get full text

An evaluation of positive behavioural support for people with very severe challenging behaviours in community-based settings by Grey, Ian M.

Get full text
Get full text
Get full text
Get full text

HER2-positive apocrine carcinoma of the breast: a population-based analysis of treatment and outcome by Faruk Skenderi (6616190)

“…HER2+/SR−/APO had a significantly lower histological grade than the HER2+/SR−/NST (p < 0.001). …”

Addition of sphingosine-1-phosphate to human oocyte culture medium decreases embryo fragmentation by Zreik, Tony

Get full text
Get full text
Get full text

Evaluating the impact of a brief Health at Every Size-informed health promotion activity on body positivity and internalized weight-based oppression by Lily, O’Hara

“…The aim of this study was to evaluate the impact of a brief health promotion activity informed by Health at Every Size- and critical health promotion principles on body positivity and internalized weight-based oppression in female students at Qatar University. …”
Get full text
Get full text
Get full text

The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... by Wesal Habbab (17346961)

“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”

Decreased Analgesic Requirements in Super Morbidly Versus Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy by Hamed Elgendy (14148846)

Structure-activity relationships of copper-based metal-organic Frameworks: Investigating antibacterial mechanisms against gram-positive and gram-negative bacteria by Muhammad Hubab (20639153)

“…<u>Transmission Electron Microscopy</u> (TEM) analysis verified the significant <u>biocidal</u> activity of Cu-MOFs against both the Gram-negative (<i><u>Escherichia coli</u></i>) and Gram-positive (<u>Staphylococcus aureus</u> and <i>Bacillus subtilis</i>) bacteria, by disrupting their cell membranes and inducing cell death primarily through Cu²⁺ <u>ion release</u>. …”

Structure-Activity Relationships of Copper-Based Metal-Organic Frameworks: Investigating Antibacterial Mechanisms against Gram-Positive and Gram-Negative Bacteria by Muhammad Hubab (20639153)

“…Transmission Electron Microscopy (TEM) analysis verified the significant biocidal activity of Cu-MOFs against both the Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus and Bacillus subtilis) bacteria, by disrupting their cell membranes and inducing cell death primarily through Cu²⁺ ion release. …”

Hemodynamics of small aneurysm pairs at the internal carotid artery by Jou, Liang-Der

“…The maximum wall shear stress increases for serial aneurysms, but decreases for parallel aneurysms. Interaction between parallel aneurysms is not significant; however, the proximal aneurysm in serial aneurysms may be subject to a greater rupture risk.…”
Get full text
Get full text
Get full text
Get full text

Optimizing patellar positioning during total knee arthroplasty by Deeb, Mary

“…Medialization of the prosthetic patella has been recommended; however, no evidence-based guidelines have been reported. Material and method This anatomical study aims to quantify a pre-defined optimal location for positioning of the patellar component with regard to the centre of the patellar cut. …”
Get full text
Get full text
Get full text

Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser by Salem, Hayder

Get full text

Applications of bioconvection for tiny particles due to two concentric cylinders when role of Lorentz force is significant by Lei Zhang (38117)

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”

The Conceptualization, Perceptions, and Practice of Positive Education in University Student Accessibility Departments by KARAKI, SUHA

“…This emphasizes the significance of this study, since it provides suggestions for a relevant framework that can be used in student accessibility departments in higher education through uncovering conceptualization, practice and perceptions of positive education.…”
Get full text