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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Monitoring the variation of soil quality with sewage sludge application rates in absence of rhizosphere effect
Published 2020“…The dose-dependent improvement of organic matter content was the most significant event that reflected sludge application rates, and consequently influenced other soil properties. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
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Effect of the stretch rate during uniaxial testing on the mechanical properties of prolene
Published 2017“…No statistically significant dependence of peak load on stretch rate was found. …”
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A FeedForward–Convolutional Neural Network to Detect Low-Rate DoS in IoT
Published 2022“…One such threat to a network is the Low-Rate Denial of Service (LR DoS) attack, where the attacker sends precise traffic bursts that force a TCP flow to enter a retransmission timeout state. …”
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
Published 2006Get full text
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
Published 2025“…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…”
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SWIPT-Enabled Relaying Networks for Next-Generation Wireless Systems: A Review of Achievable Rates and Future Challenges
Published 2025“…Among its various applications, relaying networks represent a key area in which SWIPT can make a significant impact. …”
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Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through...
Published 2021“…Results The method of measuring reflectivity is good to excellent reliability for all regions of interest except the fourth. The mean reflectivity of the choriocapillaris and Sattler’s layer in amblyopic eyes were significantly lower than in healthy eyes (p = 0.003 and p = 0.008 respectively). …”
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Measuring LEED–NC applicability in design for hospitality
Published 2015“…Research was conducted to determine precisely which green building innovations present the most significant barriers to incorporating sustainability into design for hospitality. …”
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Assessing uncertainty in image-based monitoring: addressing false positives, false negatives, and base rate bias in structural health evaluation
Published 2025“…However, its reliability is impacted by challenges such as false positives, false negatives, and environmental variability, particularly in low base rate damage scenarios. The Base Rate Bias plays a significant role, as low probabilities of actual damage often lead to misinterpretation of positive results. …”
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Pyrolysis of biosolids with waste cardboard: effect of operating parameters, feedstock size and blending ratio
Published 2023“…For future applications, temperatures below 550 °C can be considered in terms of biochar yield, ash, and metal contents; as heating rate and residence time showed minimal effects on yield, lower points are preferred to conserve energy during pyrolysis. …”
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