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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Landscape of childhood epilepsies – A multi-ethnic population-based study
Published 2022“…Risk factors associated with an increased risk of co-morbidities and intractable epilepsy included early age of epilepsy onset (< 2 years of age); etiology; antenatal risk factors; history of previous central nervous system infection; history of status epilepticus and a family history of consanguinity and epilepsy. </p><h3>Significance </h3><p dir="ltr">This large multi-ethnic population-based study confirms that the prevalence, incidence and clinical features of epilepsy in Qatar is in accordance with other epidemiologic studies and highlights risk factors for the development of co-morbidities and medically-intractable epilepsy.…”
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Maternal and Neonatal Outcomes Post Bariatric Surgery: A Population-Based Study
Published 2023“…</p> <h3>Design</h3> <p>This population-based study was conducted using 12-month retrospective registry data from the PEARL-Peristat Study at the Women's Wellness and Research Center (WWRC) in Qatar.…”
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Prevalence, predictors, and outcomes of major congenital anomalies: A population-based register study
Published 2023“…We aimed to assess the incidence, risk factors, and outcomes of major CAs in the State of Qatar. A population-based retrospective data analysis of registry data retrieved from the Perinatal Neonatal Outcomes Research Study in the Arabian Gulf (PEARL-Peristat Study) between April 2017 and March 2018. …”
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Population based treatment strategy of H pylori in Qatar: Through clinical and demographic insights
Published 2024“…<h3>Background and study aim </h3><p dir="ltr"><i>Helicobacter Pylori (H. pylori)</i>, a widespread gastric pathogen, can have a range of presentations necessitating population based tailored treatment strategies. We aimed to study the clinical and demographic profile of patients with H pylori in Qatar, to determine the best treatment strategy for Qatar’s population. …”
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A customised fetal growth and birthweight standard for Qatar: a population-based cohort study
Published 2024“…<h3>Objectives</h3><p dir="ltr">Customized birthweight centiles have improved the detection of small for gestational age (SGA) and large for gestational age (LGA) babies compared to existing population standards. …”
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Maternal vaccine hesitancy towards COVID-19 immunisation of children in Qatar: a population-based cross-sectional study
Published 2022“…</p> <h3>Methods</h3> <p>A population-based, online cross-sectional survey was conducted between 15 October and 15 November 2020. …”
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Salivary microbiome and hypertension in the Qatari population
Published 2023“…Machine Learning (ML) strategies were applied to identify salivary microbiome-based predictors of hypertension.</p><h3>Results</h3><p dir="ltr">Differential abundant analysis (DAA) revealed thatBacteroidesand Atopobiumwere the significant members of the hypertensive groups. …”
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Trends in Necrotizing Fasciitis‐Associated Mortality in the United States 2003–2020: A CDC WONDER Database Population‐Based Study
Published 2025“…</p><h3>Conclusions</h3><p dir="ltr">NF‐related mortality has significantly risen in the United States since 2014, with distinct disparities based on sex, race, and geographic region. …”
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Mining exposes Sudanese population to harmful pollutants
Published 2015“…The Blue Nile State has an economy based largely on agriculture and livestock, and approximately three quarters of the population inhabit rural areas. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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The Development And Significance Of Business Intelligence (BI) Platforms In Facilitating The Decision-Making Process In Dubai Government Entities
Published 2022“…Thus, the current study has focused on analysing the significance of BI platforms in improving the decision-making process in the Dubai Statistics Center (DSC), a governmental entity in Dubai. …”
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