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Patients with early onset of type 1 diabetes have significantly higher GG genotype at position 49 of the CTLA4 gene
Published 2004“…The GG genotype was also significantly higher among patients (12.6%) than in controls (4.2%). χ2 analysis and family-based association studies were performed and suggested the association of CTLA4 exon 1 G polymorphism with T1D (p = 0.0229). …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Assessing uncertainty in image-based monitoring: addressing false positives, false negatives, and base rate bias in structural health evaluation
Published 2025“…The Base Rate Bias plays a significant role, as low probabilities of actual damage often lead to misinterpretation of positive results. …”
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HER2-positive apocrine carcinoma of the breast: a population-based analysis of treatment and outcome
Published 2022“…HER2+/SR−/APO had a significantly lower histological grade than the HER2+/SR−/NST (p < 0.001). …”
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Evaluating the impact of a brief Health at Every Size-informed health promotion activity on body positivity and internalized weight-based oppression
Published 2021“…The aim of this study was to evaluate the impact of a brief health promotion activity informed by Health at Every Size- and critical health promotion principles on body positivity and internalized weight-based oppression in female students at Qatar University. …”
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Structure-activity relationships of copper-based metal-organic Frameworks: Investigating antibacterial mechanisms against gram-positive and gram-negative bacteria
Published 2025“…<u>Transmission Electron Microscopy</u> (TEM) analysis verified the significant <u>biocidal</u> activity of Cu-MOFs against both the Gram-negative (<i><u>Escherichia coli</u></i>) and Gram-positive (<u>Staphylococcus aureus</u> and <i>Bacillus subtilis</i>) bacteria, by disrupting their cell membranes and inducing cell death primarily through Cu<sup>2+</sup> <u>ion release</u>. …”
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Structure-Activity Relationships of Copper-Based Metal-Organic Frameworks: Investigating Antibacterial Mechanisms against Gram-Positive and Gram-Negative Bacteria
Published 2025“…Transmission Electron Microscopy (TEM) analysis verified the significant biocidal activity of Cu-MOFs against both the Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus and Bacillus subtilis) bacteria, by disrupting their cell membranes and inducing cell death primarily through Cu<sup>2</sup><sup>+</sup> ion release. …”
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A component analysis of positive behaviour support plans
Published 2012“…Background Positive behaviour support (PBS) emphasises multi-component interventions by natural intervention agents to help people overcome challenging behaviours. …”
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Optimizing patellar positioning during total knee arthroplasty
Published 2017“…Medialization of the prosthetic patella has been recommended; however, no evidence-based guidelines have been reported. Material and method This anatomical study aims to quantify a pre-defined optimal location for positioning of the patellar component with regard to the centre of the patellar cut. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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The Conceptualization, Perceptions, and Practice of Positive Education in University Student Accessibility Departments
Published 2023“…This emphasizes the significance of this study, since it provides suggestions for a relevant framework that can be used in student accessibility departments in higher education through uncovering conceptualization, practice and perceptions of positive education.…”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
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The Impact of Adopting Positive Education and Wellbeing Culture on Learners with Special Educational Needs and Disabilities (SEND) in a Private and Mainstream School in Dubai: An E...
Published 2020“…The impact of positive education and wellbeing culture on learners with special educational needs and disabilities (SEND) in Dubai-based inclusive schools has been an active area of education research. …”
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The Association between Benefits Realization and Dubai/UAE Infrastructure Development Projects Outcomes
Published 2018“…Findings: The results of the research provided that there is significant positive relationship between Benefits Realization and UAE Infrastructure development project outcomes along with a significant positive relationship between UAE Infrastructure development project outcomes and Identifying Benefits. …”
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Identity and Aggregate Signature-Based Authentication Protocol for IoD Deployment Military Drone
Published 2021“…It is of critical significance given the advancement in modern strategic narratives. …”
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Sex differences in shoulder performance fatiguability are affected by arm position, dominance and muscle group
Published 2022“…There was a significant difference between the ER and IR muscles, with significantly higher values observed for the IR in C.Perf (mean difference = 331.74 J) by 30.0% and in BR (mean difference = 13.31 J) by 26.64%. …”
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
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