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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems
Published 2021“…</p><h3>Conclusions</h3><p dir="ltr">Our subnational estimates of HIV mortality revealed significant spatial variation and diverging local trends in HIV mortality over time and by age. …”
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Hedonic valuation of land protection methods: implications for cluster development.
Published 2014“…The key findings of the study are: (i) proximity to national or state park land and to city or county open space has a significant positive impact on property values, while proximity to national forest land or to privately conserved land exhibits no significant effects; and, (ii) inclusion of a property within a cluster development decreases its value by 17 to 26 %. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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Designing a Flexible and Reconfigurable Manufacturing System Considering a Circular Shaped Layout
Published 2018Get full text
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Engineering PLA-MXene nanocomposite with balanced mechanical properties for enhanced shape memory effect
Published 2024“…The PLA/Mx composite exhibited a significantly improved shape memory effect than the PLA alone. …”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
Published 2008Get full text
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Role of Active Morphing in the Aerodynamic Performance of Flapping Wings in Formation Flight
Published 2021“…This arrangement enables an increase in the overall efficiency of the group because the wake vortices shed by each of the birds provide additional lift and thrust to every member. …”
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Double diffusive mixed convection and entropy generation analysis of NEPCM-water mixture in a π-shaped cavity
Published 2025“…Results demonstrate that Reynolds and Richardson numbers significantly enhance heat and mass transfer (up to 204 % increase in Nusselt number), while magnetic fields substantially suppress convective transport (60.5 % reduction in Nusselt number). …”
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
Published 2006Get full text
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Design, Implementation, and Performance Analysis of Actively
Published 2023Get full text
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FEA Investigation of Elastic Buckling for Functionally Graded Material (FGM) Thin Plates with Different Hole Shapes under Uniaxial Loading
Published 2022“…Moreover, the lower the power law index, the higher the critical buckling load. The diamond shape opening shows the best performance in terms of the critical buckling load, and the effect of the plate thickness has a more significant influence on the critical buckling load of the FGM plate compared to the size of the opening.…”
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Enhanced natural convection in a U-shaped baffled cavity: Synergistic effects of magnetic fields and wall oscillations on Nano-encapsulated PCM
Published 2025“…Nanoparticle volume fraction also significantly enhances heat transfer, with a 58.9 % increase in Nusselt number as <i>ϕ</i> increases from 0.01 to 0.04. …”
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
Published 2025“…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…”
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Numerical Investigation of Flexural Behavior of Reinforced Concrete (RC) T-Beams Strengthened with Pre-Stressed Iron-Based (FeMnSiCrNi) Shape Memory Alloy Bars
Published 2023“…Based on the numerical results, it was found that increasing the compression strength from 30 to 60 MPa slightly improves the beam’s strength (by 2%), but it significantly increases its ductility by approximately 45%. …”
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