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Adaptive response for climate change challenges for small and vulnerable coastal area (SVCA) countries: Qatar perspective
Published 2023“…Along with mitigation efforts, adaptive response actions are gaining increasingly urgent importance for many regions to considerably reduce the most severe impacts of climate change on social and physical infrastructure. As the severity and frequency of climate change impacts and consequences grow fast and highly alarming, particularly for small and vulnerable coastal area (SVCA) countries, the urgency and magnitude of the crises call for immediate and more adaptive responses. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Unveiling the Nexus Between Land Use, Land Surface Temperature, and Carbon Footprint: A Multi-Scale Analysis of Building Energy Consumption in Arid Urban Areas
Published 2024“…<p dir="ltr">Urbanization and land use changes, especially in arid environments, significantly impact local climate and energy demand. …”
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Solid waste treatment opportunities in the Palestinian authority areas
Published 2008“…The results of the survey conducted in 2001–2002 were later reviewed during July–October 2008 to assess if the trend of domestic solid waste generation had changed. Based on the survey and post-assessment, it is found that political and economic conditions have both significantly impacted the trend of generated municipal solid waste and since no improvements in either condition are forthcoming, it is concluded that survey results could be used in a planning study. …”
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Conceptual Skills in Leading Change: A Competence Approach to Public Sector Leadership
Published 2019“…The thesis concludes on the significance of individuals’ conceptual skills in leading public sector change by presenting a framework of conceptual skills relevant to four areas of leadership: self-regulation, sensemaking, integrative leadership and innovative leadership. …”
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Internet Searches for Medical Symptoms Before Seeking Information on 12-Step Addiction Treatment Programs: A Web-Search Log Analysis
Published 2019“…Specifically, symptom queries were first determined to be significantly predictive of subsequent 12-step queries if the probability of querying a medical symptom by those who later sought information about the 12-step program exceeded the probability of that same query being made by a comparison group of all other Bing users in the United States. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…”
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Land surface temperature responses to land use dynamics in urban areas of Doha, Qatar
Published 2024“…The analysis of land use and land cover changes reveals a remarkable 343.16 % increase in the built-up area from 2000 to 2023, at the expense of previously existing desert lands and water bodies. …”
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Land surface temperature responses to land use dynamics in urban areas of Doha, Qatar
Published 2024“…The analysis of land use and land cover changes reveals a remarkable 343.16 % increase in the built-up area from 2000 to 2023, at the expense of previously existing desert lands and water bodies. …”
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