Neoadjuvant Chemotherapy Alters Neuropilin-1, PlGF, and SNAI1 Expression Levels and Predicts Breast Cancer Patients Response by Noura Al-Zeheimi (5177066)

“…<i>SNAI1</i> expression in immune cells showed a significant increase (<i>p</i> = 0.018) in patients with pCR, consistent with its posited protective role. …”

Detection of statistically significant network changes in complex biological networks by Raghvendra Mall (581171)

“…</p><h3>Methods</h3><p dir="ltr">In this paper, we propose an improvement over the state-of-the-art based on the Generalized Hamming Distance adopted for evaluating the topological difference between two networks and estimating its statistical significance. The proposed procedure exploits a more effective model selection criteria to generate <i>p</i>-values for statistical significance and is more efficient in terms of computational time and prediction accuracy than literature methods. …”

Decreased Analgesic Requirements in Super Morbidly Versus Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy by Hamed Elgendy (14148846)

Serum immune mediators as novel predictors of response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer patients with high tissue-PD-L1 expression by Afsheen Raza (492657)

“…Moreover, correlation analysis showed significant positive linear correlation of soluble PD-L1 (sPD-L1) with higher TPD-L1 expression. …”

L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression by Rached, Johnny

Get full text
Get full text
Get full text
Get full text

Analysis of facial emotion expression in eating occasions using deep learning by Elif Yildirim (17725965)

“…We propose a facial expression-based prediction model to eliminate user bias in questionnaire-based assessment systems and to minimize false entries to the system. …”

Deep learning-based modeling of land use/land cover changes impact on land surface temperature in Greater Amman Municipality, Jordan (1980–2030) by Khaled F. Alkaraki (22051967)

“…This study aimed to model past, present, and future LULCC on Land Surface Temperatures in the Greater Amman Municipality (GAM) in Jordan between 1980 and 2030. …”

Novel Synonymous Variant in<i> IL7R</i> Causes Preferential Expression of the Soluble Isoform by Rafah Mackeh (14151225)

“…</p><h3>Conclusion</h3><p dir="ltr">In this study, we identified a novel rare synonymous mutation causing a loss of IL-7Rα expression at the cellular membrane. This case demonstrates the value of reanalyzing genetic data based on the clinical phenotype and highlights the significance of functional studies in determining the pathogenicity of genetic variants.…”

Comprehensive analysis of circulating miRNA expression profiles in insulin resistance and type 2 diabetes in Qatari population by Khaoula Errafii (10914446)

Contrasting and Predicting Social Media’s Role in Addictive Use and Well-Being by Deniz Cemiloglu (17150980)

“…Competence in using social media significantly predicted both PSMU and SM-WB in the Arab sample. …”

An ant colony optimization algorithm to improve software quality prediction models by Azar, D.

“…As a result, the prediction models built on one data set show a significant deterioration of their accuracy when they are used to classify new, unseen data. …”
Get full text
Get full text
Get full text

iPSC-Derived Pancreatic Progenitors Lacking FOXA2 Reveal Alterations in miRNA Expression Targeting Key Pancreatic Genes by Noura Aldous (15429873)

“…RNA sequencing analysis demonstrated significant reduction in the mRNA expression of genes involved in the development and function of exocrine and endocrine pancreas. …”

Cross-sectional proteomic expression in Parkinson's disease-related proteins in drug-naïve patients vs healthy controls with longitudinal clinical follow-up by Ilham Yahya Abdi (17870462)

“…Among the DEPs identified, eight proteins—ALCAM, contactin 1, CD36, DUS3, NEGR1, Notch1, TrkB, and BTK— significantly correlated with longitudinal clinical scores including motor and non-motor symptom scores, cognitive function and depression scales, indicating potential predictive values for progression in PD among various phenotypes. …”

MicroRNA Expression Profiling on Paired Primary and Lymph Node Metastatic Breast Cancer Revealed Distinct microRNA Profile Associated With LNM by Ramesh Elango (7542068)

“…Interestingly, interrogation of the expression levels of hsa-miR-205 and hsa-miR-214 in the METABRIC breast cancer dataset revealed significantly poor overall survival in patients with downregulated expression of miR-205 [HR = 0.75 (0.61–0.91)], p = 0.003 and hsa-miR-214 [HR = 0.74 (0.59–0.93) p = 0.008]. …”

Epigenetic analysis of Paget’s disease of bone identifies differentially methylated loci that predict disease status by Ilhame Diboun (3522413)

“…Meta-analysis of data from the discovery and cross-validation set, each comprising 116 PDB cases and 130 controls, revealed significant differences in DNA methylation at 14 CpG sites, 4 CpG islands, and 6 gene-body regions. …”

Squamous Cell Carcinomas of the Head and Neck Cancer Response to Programmed Cell Death Protein-1 Targeting and Differential Expression of Immunological Markers: A Case Report by Maysaloun Merhi (4246147)

“…The search for biomarkers of response is a strategy to predict response and outcome of PD-1/PD-L1 checkpoint intervention. …”

Malignant peritoneal mesothelioma interactome with 417 novel protein–protein interactions by Kalyani B. Karunakaran (12478431)

“…The MPeM interactome overlapped significantly with the malignant pleural mesothelioma interactome, revealing shared molecular pathways.…”

Visitors off the trail: Impacts on the dominant plant, bryophyte and lichen species in alpine heath vegetation in sub-arctic Sweden by Monika, Rawat

“…With a greater decrease in taller forbs and shrubs than in graminoids and prostrate plants, a greater decrease in lichen than in bryophyte species, and a change in vegetation composition. …”
Get full text
Get full text
Get full text

Effect of consanguinity on birth weight for gestational age in a developing country by Wakim, Gerard

“…No significant difference was observed in the decrease in birth weight between the first- and second-cousin marriages. …”
Get full text
Get full text
Get full text
Get full text

Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance by Zouhaier Farhani (22330693)

“…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…”