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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Both decreasing interstructural space size and increasing total cover increase shrimp abundance on artificial structures deployed in a UAE seagrass bed
Published 2015“…This is the first study demonstrating possible seasonal differences in UAE seagrass fauna.…”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Using Unilateral Strength, Power and Reactive Strength Tests to Detect the Magnitude and Direction of Asymmetry: A Test-Retest Design
Published 2019“…Within and between-session reliability ranged from moderate to excellent (ICC range = 0.70–0.96) and CV values ranged from 3.7–13.7% across tests. Significant differences in asymmetry between test sessions were seen for impulse during the isometric squat (p = 0.04; effect size = –0.60) but only when calculating from the best trial. …”
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Differences in Player Position Running Velocity at Lactate Thresholds Among Male Professional German Soccer Players
Published 2019“…Players completed a treadmill test, at incremental speeds, to determine running velocity at different blood lactate concentrations (v2 = 2 mmol/l; v4 = 4 mmol/l; and v6 = 6 mmol/l). …”
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Gender differences in personal values
Published 2015“…Purpose – The purpose of this paper is to explore gender differences in personal values in an Arab country. Design/methodology/approach – Based on a sample of 137 participants, the Kruskal-Wallis test was used to identify if the mean scores or ranks of personal values scores were significantly different between males and females. …”
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Effect of the stretch rate during uniaxial testing on the mechanical properties of prolene
Published 2017“…Uniaxial tensile testing was performed on mesh samples on a universal testing machine and involved loading different samples at 5 cross-head speeds of: 1, 10, 50, 100, and 500 mm/min. …”
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Effect of corporate ethics and social responsibility on OCB: the role of employee identification and perceived CSR significance
Published 2021“…The proposed model depicting the relationships is tested empirically based on data collected from a survey instrument distributed to alumni from one of the leading universities in Lebanon employed in various companies belonging to different sectors in Lebanon and the region. …”
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Dynamic Properties of Soil in UAE from Field and Laboratory Tests
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Relationship Between the Critical Power Test and a 20-min Functional Threshold Power Test in Cycling
Published 2021“…<div><p>To investigate the agreement between critical power (CP) and functional threshold power (FTP), 17 trained cyclists and triathletes (mean ± SD: age 31 ± 9 years, body mass 80 ± 10 kg, maximal aerobic power 350 ± 56 W, peak oxygen consumption 51 ± 10 mL⋅min–1⋅kg–1) performed a maximal incremental ramp test, a single-visit CP test and a 20-min time trial (TT) test in randomized order on three different days. …”
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FE modeling of concrete beams and columns reinforced with FRP composites
Published 2021“…In the second part of this research, flexural behavior of RC beams reinforced with BFRP, GFRP and CFRP bars is investigated along with validation of the numerical model with the experimental tests. The results resembled the experimental observations that indicate significant effect of the FRP bar diameter and type ont he flexural capacity of the RC beams. …”
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