-
1
A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
-
2
-
3
-
4
Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…”
-
5
-
6
Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
-
7
The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
-
8
-
9
Predictors of diabetes fatalism among Arabs
Published 2018“…Age (β = −.14, 95% CI −.27, −.002), BMI (β = .35, 95% CI .15; .54), level of education (β = −3.98, 95% CI −7.64; −.32) and number of diabetes problems (β = −5.03, 95% CI −9.89; −.18) were significantly associated with diabetes fatalism in the regression model. …”
Get full text
Get full text
Get full text
Get full text
article -
10
Predictors of Clinical Outcomes in Autologous Cranioplasty
Published 2022“…In bivariate analysis, pre-cranioplasty GOS good grades 4 and 5 (P < 0.001), trauma as an indication for decompressive craniectomy (DC) (P < 0.001), and early cranioplasty ≤12 weeks (P = 0.023) were statistically significant predictors for post-cranioplasty neurologic recovery at follow-up. …”
-
11
-
12
Predictors and outcomes of patient safety culture in hospitals
Published 2011“…Bivariate and mixed model regression analyses were used to examine the association between the patient safety culture predictors and outcomes. …”
Get full text
Get full text
Get full text
article -
13
Predictors of Arab American adolescent tobacco use
Published 2006“…Experimentation with narghile was 27%; it increased from 23% at 14 years to 40% at 18 years. All trends were significant (p < .001). Logistic regression analyses found ten predictors for ‘smoked a cigarette in past 30 days’ and nine and seven, respectively, for ‘ever smoked a cigarette or narghile’. …”
Get full text
Get full text
Get full text
article -
14
Predictors of neurodevelopmental outcome for preterm infants with brain injury
Published 2009“…Factors correlating with Bayley II scores at 12 and 18 months included head circumference, results of neurological and magnetic resonance imaging (MRI) examination at baseline, environmental factors such as mother–infant interactions and levels of parental stress, and infant medical factors such as Apgar scores at 5 min and length of hospital stay. Multiple regression analyses distinguished the most significant predictors of mental and motor development. …”
Get full text
Get full text
Get full text
Get full text
article -
15
Body Shape Index Is a Stronger Predictor of Diabetes
Published 2019“…ABSI is a better predictor for the risk of diabetes than BMI after the adjustment for age, gender, education, and physical activity.…”
-
16
Procrastination on social media: predictors of types, triggers and acceptance of countermeasures
Published 2021“…Several predictors such as self-control and conscientiousness were found to be significant predictors, but overall, the amount of variance explained by the regression models was relatively low. …”
-
17
Being an older refugees in Türkiye: predictors of mental health and quality of life
Published 2025“…The data were analyzed through ordinal and linear regression models, and significant predictors were identified.…”
-
18
Prospective study of incidence and predictors of peripheral intravenous catheter-induced complications
Published 2014“…Removal time for PIVCs insertion was not a significant predictor of phlebitis (RR =1.46, P=0.08). …”
Get full text
Get full text
Get full text
Get full text
article -
19
Incidence, predictors and severity of adverse events among whole blood donors
Published 2017“…Results Incidence of adverse events found 1.1% (208 donors), of which 0.65% had mild symptoms (chills; nausea; pallor; dizziness; nervousness; headache), while 0.45% had severe symptoms (hypotension; convulsions; syncope; respiratory distress; emesis). Multiple logistic regression showed that, the incidence of adverse events was significantly higher among young age donors <30 years RR[95%CI] = 1.58[1.18–2.12], p < 0.002, higher hemoglobin levels RR[95%CI] = 1.30[1.15–1.46], lower weight donors <75kg RR[95%CI] = 1.71[1.29–2.27], p <0.001 and first time donors RR[95%CI] = 2.21[1.64–2.97], p < 0.001 compared to older age donors ≥30, lower hemoglobin levels, heavier weight donors ≥ 75, and previous donors, respectively. …”
Get full text
Get full text
Get full text
Get full text
article -
20
Health-related quality of life as a predictor of tuberculosis treatment outcomes in Iraq
Published 2015“…In a direct logistic regression model, only the FACIT-TB total score made a statistically significant contribution towards predicting the likelihood that a patient would have a favourable TB treatment outcome. …”
Get full text
Get full text
Get full text
article