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Comparative assessment of fracture risk among osteoporosis and osteopenia patients: a cross-sectional study
Published 2018“…</p><h3>Results: </h3><p dir="ltr">Patients with osteoporosis had significantly higher risk of major fracture compared to patients with osteopenia (p<0.01). …”
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Direct Oral Anticoagulants Compared to Warfarin in Patients with Intermediate‐ to High‐Risk Pulmonary Embolism: A Systematic Review and Meta‐Analysis
Published 2025“…<h3>Introduction</h3><p dir="ltr">Despite recent advances in clinical therapeutics in patients with venous thromboembolism, uncertainty remains regarding the optimal anticoagulation strategy in patients with intermediate‐ to high‐risk pulmonary embolism. We aimed to evaluate the direct oral anticoagulants’ effectiveness and safety compared to warfarin in patients with intermediate‐ and high‐risk pulmonary embolism.…”
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Risk Assessment in Construction Projects: Integrating Five Dimensions of Risk
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”
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Drivers obesity and road crash risks in the United States
Published 2015“…The prevalence of class I obesity increased from 10% in 1999 to 14% in 2012 (aPR=1.50, 95% confidence intervals [95%CI]=1.42-1.58), class II obesity from 3% to 5% (aPR=2.22, 95%CI=2.05-3.01), and class III obesity from 1% to 2% (aPR=2.65; 95%CI=2.27-3.10). Compared to non-obese controls, obese drivers had significantly higher risks for fatality (1.10≤aOR≤1.47), seat-belt non-use (1.00≤aOR≤1.21), need for extrication (1.01≤aOR≤1.23), and ambulance transport time ≥30min (1.01≤aOR≤1.28). …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
Published 2025“…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”
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Compared to What? Is BMI Associated with Histopathological Changes in Laparoscopic Sleeve Gastrectomy Specimens?
Published 2019“…When confounders were taken into account, there appeared no significant associations between the BMI of patients with specific benign or pre-malignant histopathology compared with the BMI of the rest of the patients with abnormal histopathologies and compared to the BMI of patients with normal histopathologies of their gastric specimens. …”
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Sugar-Sweetened Beverages Contribute Significantly to College Students’ Daily Caloric Intake in Jordan: Soft Drinks Are Not the Major Contributor
Published 2019“…A significant positive relationship was found in BMI (p = 0.006) and waist circumference (p = 0.030) for participants consuming calories from SSBs. …”
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Qatar’s immigrants at higher risk of diabetes
Published 2015“…The researchers stress, however, that their preliminary results should be confirmed in future studies involving larger numbers of participants. 1 “We would advise the Qatari government to screen all immigrants entering the country, as this would decrease the risk of unnecessary complications due to the late diagnosis of diabetes,” says lead author Dennis Mook-Nakamori. …”
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Patients with early onset of type 1 diabetes have significantly higher GG genotype at position 49 of the CTLA4 gene
Published 2004“…The CTLA4 G allele was found to be more frequently present in patients with T1D (32.4%) as compared with its frequency in control individuals (24.5%). …”
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Multivariate epidemiologic analysis of type 2 diabetes mellitus risks in the Lebanese population
Published 2014“…Exercise activity level negatively correlated with the disease (p = 0.002), whereas the prevalence of T2DM (p < 0.0001) and CAD family history (p = 0.006) positively correlated with the affection status. The mean levels of triglycerides and LDL-C were significantly higher in diabetics (1.87; 1.35) compared to individuals with prediabetes (1.63; 1.26) and unaffected controls (1.49; 1.19). …”
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The public’s risk perception of blood transfusion in Saudi Arabia
Published 2018“…Results The overall percentage mean score±SD of risk perception was 59.8±16.1. Male participants were significantly more likely to perceive blood transfusion negatively, both in terms of the dread/severity domain (β=−0.23, p=0.003) and their overall risk perception score (β=−0.17, p=0.028). …”
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