The multiomics analyses of cancer stem cells isolated from solid tumors can provide insight for their immunological characterization. by Neha Gopinath (15431052)

Decreased Analgesic Requirements in Super Morbidly Versus Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy by Hamed Elgendy (14148846)

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”

L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression by Rached, Johnny

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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”

Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications by Sumama Nuthana Kalva (17302906)

“…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”

Both decreasing interstructural space size and increasing total cover increase shrimp abundance on artificial structures deployed in a UAE seagrass bed by Bartholomew, Aaron

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Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Vijay Ganji (8710491)

The Impact of Leadership Styles on Improving Employee Agility: The Mediating Role of Employee Incentives by ALNEYADI, EISA

“…Analyses of the direct relationships suggest that transformational leadership style has a significant impact on employee agility. …”
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Audit committee chair effectiveness and firm performance: The mediating role of sustainability disclosure by Ahmad Yuosef Alodat (17900027)

“…The study investigated the indirect impact of the mediating role in the SD index. We manually analysed 405 annual reports of the companies listed on the ASE from 2014 to 2018. …”

Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy by Jia-Zhen Wu (6844793)

“…In both cell-free and cellular models of α-synuclein aggregation, after administration of DHM and Sal B, we observed significant inhibition of α-synuclein accumulation and aggregation. …”

Achieving the sustainable development goals in developing countries: The role of remittances and the mediating effect of financial inclusion by Karim Barkat (17823665)

“…While previous literature has acknowledged the potential of remittances in fostering growth, empirical analyses on their impact on SDGs remain scant. Utilizing data from 109 developing countries spanning 2000 to 2022 and employing system GMM and the Lewbel's (2012) estimator to tackle endogeneity issues, we unveil significant positive effects of remittances on SDGs. …”

The Mediation Roles of Coping Modalities on the Relationship Between Stress and Quality of Life Among Jordanian Nurses by Wafa’a Ta’an (19065655)

“…The results showed that coping significantly mediated the relationship between stress and QOL with variations between PFC and EFC. …”

INTRAPRENEURIAL PERSONALITY AND INDIVIDUAL INNOVATION BEHAVIOUR IN SERVICE ORGANISATIONS: NETWORK BUILDING ABILITY AS A MEDIATOR by Nasaj, Mohamed

“…A quantitative research meth odology was adopted with 410 questionnaires collected from employees in the UAE service sector and subsequently analysed using structural equation modelling. The research found a significant direct relationship between intrapreneurial personality and the idea realisation stage and no direct relationship between idea generation and idea promotion. …”
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The mediating role of technology orientation in the relationship between risk management and performance of Dubai smart infrastructure projects by Alkaabi, Hessa

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Big Data Governance and Innovation Performance: The Mediating Role of Big Data Analytics Capabilities, and Organisational Agility by AL KAMZARI, MARYAM ALI

“…Evidence of significant serial mediation by BDACs and organisational agility between big data governance and innovation performance was also found. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment by Amal Sabouni (17046236)

“…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …”

Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through... by Masri, Oussama Samer

“…Results The method of measuring reflectivity is good to excellent reliability for all regions of interest except the fourth. The mean reflectivity of the choriocapillaris and Sattler’s layer in amblyopic eyes were significantly lower than in healthy eyes (p = 0.003 and p = 0.008 respectively). …”
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Metabolomics analyses reveal the crucial role of ERK in regulating metabolic pathways associated with the proliferation of human cutaneous T‐cell lymphoma cells treated with Glabri... by Abdul Q. Khan (14153247)

“…The present study explores the underlying mechanisms and metabolic signalling pathways associated with Glabridin mediated anti‐cancer actions in CTCL. Our results show that Glabridin significantly inhibits the growth of CTCL cells through induction of programmed cell death (PCD) such as apoptosis, autophagy and necrosis. …”