Decreased Analgesic Requirements in Super Morbidly Versus Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy by Hamed Elgendy (14148846)

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”

L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression by Rached, Johnny

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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”

Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications by Sumama Nuthana Kalva (17302906)

“…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”

Both decreasing interstructural space size and increasing total cover increase shrimp abundance on artificial structures deployed in a UAE seagrass bed by Bartholomew, Aaron

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Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Vijay Ganji (8710491)

Silver-based dressings for the prevention of surgical site infections: evidence from randomized trials by S. Younes (22254238)

“…<h3>Background</h3><p dir="ltr"><u>Surgical site infections</u> (SSIs) are a major cause of <u>postoperative complications</u>, increasing morbidity and healthcare costs. …”

Spatial modelling of contribution of individual level risk factors for mortality from Middle East respiratory syndrome coronavirus in the Arabian Peninsula by Oyelola A. Adegboye (4287826)

“…Health-care workers were significantly less likely to die from the disease compared with non-health workers [OR = 0.372, 95% CI: 0.151, 0.827]. …”

Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment by Amal Sabouni (17046236)

“…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …”

The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... by Wesal Habbab (17346961)

“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”

SARS‐CoV‐2 infection and effects of age, sex, comorbidity, and vaccination among older individuals: A national cohort study by Mai A. Mahmoud (9620657)

“…Risk of infection varied minimally by age and sex but increased significantly with coexisting conditions. …”

Incidence, risk factors and outcomes of nosocomial infection in adult patients supported by extracorporeal membrane oxygenation: a systematic review and meta-analysis by Ali Ait Hssain (9538617)

“…Secondary endpoints included time to infection, source of infection, ECMO duration, Intensive care and hospital length of stay (LOS), ECMO survival and overall survival. …”

Diabetic Foot Ulcer Detection: Combining Deep Learning Models for Improved Localization by Rusab Sarmun (17632269)

“…<p dir="ltr">Diabetes mellitus (DM) can cause chronic foot issues and severe infections, including Diabetic Foot Ulcers (DFUs) that heal slowly due to insufficient blood flow. …”

Efficacy and Safety of Colistin versus Tigecycline for Multi-Drug-Resistant and Extensively Drug-Resistant Gram-Negative Pathogens—A Meta-Analysis by Dina Abushanab (10696501)

“…We pooled odd ratios (OR) using heterogeneity-guided random or fixed models at a statistical significance of <i>p</i> < 0.05. …”

Virome-wide serological profiling reveals association of herpesviruses with obesity by Mohammad Rubayet Hasan (8602080)

“…<p>The relationship between viral infection and obesity has been known for several decades but epidemiological data is limited to only a few viral pathogens. …”

Effectiveness of pharmacist-led antimicrobial stewardship programs in perioperative settings: A systematic review and meta-analysis by Lina Naseralallah (14146465)

“…A meta-analysis was conducted using a random-effect model. </p><h3>Results </h3><p dir="ltr">Eleven studies were included in this review. …”

Hybrid Model for Detection of Cervical Cancer Using Causal Analysis and Machine Learning Techniques by Umesh Kumar Lilhore (17727684)

“…It is improved from of random forest method and mainly discovers feature subsets from the data source that are significant to assigned classification activity. The proposed model’s primary aim is to determine the importance of cervical cancer screening factors for classifying high-risk patients depending on the findings. …”

The Role of Government Hospital During the COVID-19 Pandemic by Omar Al Hasanat (18466263)

“…Additionally, 20 Powered Air Purifying Respirators significantly enhanced healthcare workers' safety.</p><h3>Conclusion</h3><p dir="ltr">The comprehensive strategy, and strict infection prevention measures, significantly improved patient care and healthcare workers’ safety during the COVID-19 response. …”