Decreased Analgesic Requirements in Super Morbidly Versus Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy by Hamed Elgendy (14148846)

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”

L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression by Rached, Johnny

Get full text
Get full text
Get full text
Get full text

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”

Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications by Sumama Nuthana Kalva (17302906)

“…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”

Both decreasing interstructural space size and increasing total cover increase shrimp abundance on artificial structures deployed in a UAE seagrass bed by Bartholomew, Aaron

Get full text

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Vijay Ganji (8710491)

Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment by Amal Sabouni (17046236)

“…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …”

The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... by Wesal Habbab (17346961)

“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”

Rescue cerclage by Khoury, Alfred

“…CONCLUSION: In contrast to previously reported series, our results show that rescue cerclage can result in significant pregnancy prolongation. Outcomes are not as grim as prior literature suggests, and we strongly support the consideration of rescue cerclage for these patients.…”
Get full text
Get full text
Get full text

Nursing Perception Towards Impact of JCI Accreditation and Quality of Care in a Tertiary Care Hospital, Central Saudi Arabia by Abolfotouh, Mostafa A.

“…Older (p=0.043) and less educated nurses (p=0.042) were significantly more likely to report positive perception to accreditation impact. …”
Get full text
Get full text
Get full text

Impact of staying at home measures during COVID-19 pandemic on the lifestyle of Qatar’s population: Perceived changes in diet, physical activity, and body weight by Muna Abed Alah (14779534)

“…Participants reported increased sitting/reclining time (1.94 h/day mean increase), screen times (2.05 h/day mean increase) with p < 0.001, and decreased exercise time (0.11 h/day mean reduction) with p < 0.001. …”

Surgical outcomes of laparoscopic total extraperitoneal (TEP) inguinal hernia repair compared with Lichtenstein tension-free open mesh inguinal hernia repair: A prospective randomi... by Mohammed Yunus Shah (21363248)

“…The mean operative time in group A was 84.6 ± 32.2, which was significantly higher than that in group B, 59.2 ± 14.8. …”

The Effect of HuArgI (Co)-PEG5000 on The Migration of Ovarian Cancer by El Mais, Nour

“…HuArgI (Co)-PEG5000 is a potential drug to target cancers that depend on exogenous sources of arginine and cannot synthesize their own. In this study, we hypothesized that HuArgI (Co)- PEG5000 can decrease the migration of ovarian cancer cells. …”
Get full text
Get full text
Get full text

Smoking cessation advice: the self-reported attitudes and practice of primary health care physicians in a military community, central Saudi Arabia by AlAteeq, Mohammed

“…P-values <0.05 were considered to be significant. Results Response rate was 73/150 (48.6%), of which equal sex distribution (52%:48%) was observed, with a mean age of 35.3±9.6 years. …”
Get full text
Get full text
Get full text
Get full text

Calibration of building model based on indoor temperature for overheating assessment using genetic algorithm: Methodology, evaluation criteria, and case study by Mutasim Baba, Fuad

“…Maximum Absolute Difference (MAD), a new metric, that calculates the maximum absolute difference between simulated and measured hourly indoor temperatures, Root Mean Square Error (RMSE), Normalized Mean Bias Error (NMBE) were used as the evaluation criteria. …”
Get full text
Get full text
Get full text

The relationship between addiction to smartphone usage and depression among adults: a cross sectional study by Alhassan, Aljohara A.

“…The mean ± standard deviation of their age was 31.7 ± 11  years. …”
Get full text
Get full text
Get full text
Get full text

Irritable bowel syndrome: prevalence, risk factors in an adult Lebanese population by Chatila, Rajaa

“…Results Data was collected from 553 individuals and consisted of 52.8% females (mean age 35.9 years, SD = 11.9) and 47.2% males (mean age = 36.1 years, SD = 10.3). …”
Get full text
Get full text
Get full text
Get full text

The Effect of Recombinant Anthrax Lethal Toxin on Breast Cancer Cell Motility, Adhesion, and Invasion by El Chami, Dana

“…Cells treated with LT showed a significant decrease in motility as seen in 2D time-lapse and wound healing assays. …”
Get full text
Get full text
Get full text