Decreased Analgesic Requirements in Super Morbidly Versus Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy by Hamed Elgendy (14148846)

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”

L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression by Rached, Johnny

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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”

Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications by Sumama Nuthana Kalva (17302906)

“…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”

Both decreasing interstructural space size and increasing total cover increase shrimp abundance on artificial structures deployed in a UAE seagrass bed by Bartholomew, Aaron

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Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Vijay Ganji (8710491)

Extended Preoperative Chemotherapy Does Not Improve Pathologic Response and Increases Postoperative Liver Insufficiency After Hepatic Resection for Colorectal Liver Metastases by Kishi, Yoji

“…Results Treatment consisting of ≥9 cycles was not associated with an increase in complete or major pathologic response (SD vs. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment by Amal Sabouni (17046236)

“…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …”

The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... by Wesal Habbab (17346961)

“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”

Intraocular pressure trends following intravitreal injections of anti-VEGF agents for diabetic macular edema by Al-Abdullah, Abdulelah

“…Although there was no significant difference in the baseline IOPs betweenthe IOP rise group (mean 15.76 ; SD=3.18) vs. the rest of the eyes (mean 17.34 (SD= 3.48), p: 0.071), final IOP was significantly higher in the IOP rise group (mean 18.65 vs.16.81, p 0.047). …”
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Frugal innovation for sustainable rural development by Mokter, Hossain

“…Using a grounded theory method and based on 22 interviews with key informants related to 13 cases of frugal enterprise in South Asia, this qualitative study attempts to accomplish the aim of the study. We developed a classification that identifies the increasing positive and decreasing negative parameters of SDGs to assess the extent to which frugal enterprises contribute to specific SDGs. …”
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A meta‐analysis of the educational effectiveness of three‐dimensional visualization technologies in teaching anatomy by Yammine, Kaissar

“…Based on 2,226 participants including 2,128 from studies with comparison groups, 3DVTs (1) resulted in higher (d = 0.30, 95%CI: 0.02–0.62) factual knowledge, (2) yielded significant better results (d = 0.50, 95%CI: 0.20–0.80) in spatial knowledge acquisition, and (3) produced significant increase in user satisfaction (d = 0.28, 95%CI = 0.12–0.44) and in learners' perception of the effectiveness of the learning tool (d = 0.28, 95%CI = 0.14–0.43). …”
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Validation of Polygenic Risk Scores for Coronary Heart Disease in a Middle Eastern Cohort Using Whole Genome Sequencing by Mohamad Saad (214545)

“…</p><h3>Results</h3><p dir="ltr">The majority of PRSs performed well; odds ratio (OR) per 1 SD increase (OR1sd) was highest for PGS000337 (OR1sd=1.81, 95% CI [1.66–1.98], <i>P</i>=3.07×10−41). …”

How FIFA World Cup 2022™ can meet the carbon neutral commitments and the United Nations 2030 Agenda for Sustainable Development?: Reflections from the tree nursery project in Qatar... by Ioannis Spanos (2086933)

“…</p> <h2>Other Information</h2> <p>Published in: Sustainable Development<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br> See article on publisher's website: <a href="http://dx.doi.org/10.1002/sd.2239" target="_blank">http://dx.doi.org/10.1002/sd.2239</a></p>…”

Frugal innovation for sustainable rural development by Mokter Hossain (14634969)

“…Using a grounded theory method and based on 22 interviews with key informants related to 13 cases of frugal enterprise in South Asia, this qualitative study attempts to accomplish the aim of the study. We developed a classification that identifies the increasing positive and decreasing negative parameters of SDGs to assess the extent to which frugal enterprises contribute to specific SDGs. …”

The posterior pole and papillomacular fold in posterior microphthalmos by Nowilaty, Sawsan R.

“…Conclusions The PMF in PM eyes has characteristic morphologic SD-OCT features. The increased posterior pole curvature in PM and its significant correlation with the axial length, the PMF severity and keratometry established in this study suggest that PM eyes are not only shorter than normal, but seem to be abnormally shaped posteriorly, particularly along the vertical meridian. …”
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Retinal nerve fiber layer and macular thickness in amblyopia as measured by spectral domain optical coherence tomography by Al-Haddad, Christiane E.

“…In the control group of non-amblyopic anisometropia, the interocular difference did not reach statistical significance. Conclusions Central macular thickness was significantly increased in anisometropic amblyopia using SD-OCT. …”
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The Effect of HuArgI (Co)-PEG5000 on The Migration of Ovarian Cancer by El Mais, Nour

“…HuArgI (Co)-PEG5000 is a potential drug to target cancers that depend on exogenous sources of arginine and cannot synthesize their own. In this study, we hypothesized that HuArgI (Co)- PEG5000 can decrease the migration of ovarian cancer cells. …”
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