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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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Significance of Avicennia Marina in the Arabian Gulf Environment: A Review
Published 2025“…However, in the past two decades Gulf mangroves have been facing significant threats, including extensive coastal development, shoreline modification by establishing marinas and ports, and climate change-associated impacts such as sea-level rise and altered precipitation patterns, which pose significant risks to this fragile ecosystem. …”
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Managing change process: A case study of a private school in Sharjah
Published 2016“…The significance of change process management increases as the modern world trends of education and learning require a change. …”
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Learning Organisation and Readiness for Change in Higher Education Institutions: The Intervening Role of Organizational and Individual Resilience
Published 2024“…Higher education institutions today face an increasingly complex and rapidly changing environment. …”
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Snow runoff modelling in the upper Indus River Basin and its implication to energy water food nexus
Published 2024“…This, in turn, may enhance the resilience of both the hydropower and agriculture sectors in the face of climate change.</p><h2>Other Information</h2> <p> Published in: Ecological Modelling<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.ecolmodel.2024.110871" target="_blank">https://dx.doi.org/10.1016/j.ecolmodel.2024.110871</a></p>…”
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Change detection using remote sensing in a reef environment of the UAE during the extreme event of El Niño 2015–2016
Published 2018“…While sea-surface temperature anomalies of 1°C were reported to significantly damage coral reefs around the world, the live coral habitat was observed to exhibit no-change despite four consecutive months of +2°C to 3°C anomalies reported during the study period. …”
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Teachers’ Job Satisfaction in Instructional Delivery Modalities, and the Role of School Leaders: a Study among Selected Private Schools in Abu Dhabi.
Published 2022“…The result of the data analysis confirmed that there is a significant association between the new variable, teaching modality, and teachers’ job satisfaction. …”
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Traditional irrigation knowledge for sustainable water resource management in arid Environments: Insights from the MENA region
Published 2025“…The Middle East and North Africa (MENA) region faces significant climate challenges, including low rainfall, rising temperatures, and recurrent droughts. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Hemodynamics of small aneurysm pairs at the internal carotid artery
Published 2012“…The maximum wall shear stress increases for serial aneurysms, but decreases for parallel aneurysms. Interaction between parallel aneurysms is not significant; however, the proximal aneurysm in serial aneurysms may be subject to a greater rupture risk.…”
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
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Short-term behavioural responses to thermal stress by hawksbill turtles in the Arabian region
Published 2014“…Surface waters typically exceed 30°C for sustained periods during the summer, and can be likened to a natural living laboratory for understanding thermoregulatory behaviour by marine species in the face of climate change and elevated global temperatures. …”
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Claims Management and Substantiation in the United Arab Emirates Construction Sector
Published 2012“…Some of the findings revealed in this dissertation were the importance of records keeping, formal notifications and significance of change and change orders in the context of claims management and other key aspects relevant to the field of claims management and substantiation.…”
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