A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”

Addition of sphingosine-1-phosphate to human oocyte culture medium decreases embryo fragmentation by Zreik, Tony

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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... by Wesal Habbab (17346961)

“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”

Both decreasing interstructural space size and increasing total cover increase shrimp abundance on artificial structures deployed in a UAE seagrass bed by Bartholomew, Aaron

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Decreased Analgesic Requirements in Super Morbidly Versus Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy by Hamed Elgendy (14148846)

Depression in migrant workers and nationals of Qatar: An exploratory cross-cultural study by Salma M Khaled (6742259)

“…In addition, we tested if the latter two variables moderated the effect of culture of origin on depressive symptomology in the migrant groups.…”

Pharmacist input to depression screening and management in patients with diabetes: a systematic review by Mai I. AL‑Hawamdeh (22798782)

“…All studies demonstrated the positive impact of pharmacists on depression screening, treatment initiation, and medication adherence., Some interventions failed to significantly improve clinical parameters such as HbA1c levels or depressive symptoms. …”

Citrate is Protective Against Chronic Stress in Females by Haddad, Zena

“…Treatment of MDD includes anti-depressant medication and psychotherapy. Lifestyle modifications such as adoption of a balanced diet and exercise can also have significant effects on the progression of the disease. …”
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Comparison of the Incidence and Magnitude of Hyponatremia Among Patients With Poststroke Depression Receiving Either Escitalopram or Sertraline by Lina Naseralallah (14146465)

“…<p dir="ltr">Depression is the most frequent psychiatric condition experienced in stroke survivors. …”

Screening for antenatal depression and its determinants among pregnant women in Qatar: revisiting the biopsychosocial model by Sarah Naja (9954737)

“…The prevalence of antenatal depression and significant determinants are unknown in Qatar, a gap that we propose to fill.…”

Applications of bioconvection for tiny particles due to two concentric cylinders when role of Lorentz force is significant by Lei Zhang (38117)

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”

Breastfeeding is associated with reduction in postpartum depression in the United Arab Emirates: a retrospective cross-sectional study by Ala Al Rajabi (22457746)

“…None of the remaining variables -including physical activity- were significant. …”

Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment by Amal Sabouni (17046236)

“…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …”

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”

L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression by Rached, Johnny

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Association Between Three-Months Vitamin D Supplementation and Depressive Symptomatology incidence among Saudi Arabian Adults by Khaddaj, Rashel

“…At baseline, when adjusting for age and gender only, we observed that lower vitamin D serum levels were associated with higher depression prevalence. When vitamin D was considered as continuous variable, each unit increase in vitamin D levels was associated with a lower depression prevalence (OR=0.87; 95% CI:0.79-0.95, p=0.005) and when compared to those insufficient, those deficient were 4 times more likely to suffer from depression (OR=4.47, 95% CI:1.39-14.38,p=0.012) Nevertheless, these significant results were lost with further adjustment for BMI, MeDi adherence and physical activity: continuous vitamin D: OR=0.90; 95% CI: 0.81-1.01, p=0.08, deficient versus insufficient:OR=2.18; 95% CI: 0.56-8.47,p=0.259). …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion by Khoury, Nathalie

“…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…”
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Mental health burden of conflict: rates and correlates of depressive and anxiety symptoms among displaced Palestinian children and adolescents in Qatar by Mohamed Adil Shah Khoodoruth (14589828)

“…<h3 dir="ltr">Aims</h3><p dir="ltr">To estimate the prevalence of clinically significant anxiety and depressive symptoms and to identify psychosocial and trauma-related factors associated with symptom severity in this population.…”

Social determinants of depression among mid-to-older aged Australians: A prospective study of the effects of neighbourhood disadvantage and crime by Vincent, Learnihan

“…This study examined relationships between area-level objective crime, self-reported perceptions of crime, neighbourhood disadvantage and depression, and potential mechanisms by which these variables indirectly lead to depression. …”
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