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Recent advances in the treatment and outcome of locally advanced rectal cancer
Published 1999“…Background Preoperative therapy has been used in locally advanced rectal cancer to preserve sphincter function, decrease local recurrence, and improve survival. …”
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Antibiotic use and escherichia coli resistance trends for quinolones and cotrimoxazole in Sweden
Published 2002“…At the 2 university teaching hospitals included, norfloxacin resistance of E. coli increased significantly (p< 0.001) from 0% to 2.7% and 2.5%, respectively. …”
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Exploring Unique Physiological and Genetic Features of Desert-dwelling Legumes
Published 2025“…Unfortunately, despite having significant beneficial and commercial properties, research initiatives associated with desert legumes are somewhat neglected. …”
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Microalgal-based desalination brine remediation: Achievements, challenges, and future research trends
Published 2024“…In addition, desalination plants consume significant amounts of energy, which contribute to carbon emissions and global warming. …”
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Trends of the Dementia Burden in South Asia: An Analysis of 2021 Global Burden of Disease Study
Published 2025“…</p><h3>Results</h3><p dir="ltr">A slight decrease in incidence rates from 80.57 to 79 per 100,000 was observed, alongside a significant increase in mortality rates from 14.11 to 17.2 per 100,000. …”
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Intraocular pressure trends following intravitreal injections of anti-VEGF agents for diabetic macular edema
Published 2013“…Purpose: To investigate the intraocular pressure (IOP) trends after intravitreal anti-vascular endothelial growth factor (VEGF) agents for diabetic macular edema (DME). …”
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Prevalence and global trends of polypharmacy in patients with chronic kidney disease: A systematic review and meta-analysis
Published 2023“…<h3>Background and objectives</h3><p dir="ltr"> Polypharmacy and chronic kidney disease (CKD) are becoming increasingly common due to an ageing population and the rise of multimorbidity. …”
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Endocrine contribution to the sexual dysfunction in patients with advanced chronic kidney disease and the role of hyperprolactinemia
Published 2021“…Patients treated with cabergoline (<i>n</i> = 26) showed a significant increase in LH levels (<i>p</i> = .003) and a significant decrease in prolactin levels (<i>p</i> = .003). …”
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Trends in Necrotizing Fasciitis‐Associated Mortality in the United States 2003–2020: A CDC WONDER Database Population‐Based Study
Published 2025“…Additionally, urban–rural analysis indicated that large central metropolitan areas had consistently elevated mortality rates, whereas smaller metropolitan and noncore areas experienced sharper increases.</p><h3>Conclusions</h3><p dir="ltr">NF‐related mortality has significantly risen in the United States since 2014, with distinct disparities based on sex, race, and geographic region. …”
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Emerging trends of carbon emissions and foreign direct investment: accounting for ecological footprints, renewable energy, globalization, and technological innovations in BRICS
Published 2023“…Our empirical findings underscore the following key insights: foreign direct investment, technological innovations, and the adoption of renewable energy sources significantly contribute to the mitigation of carbon emissions in these selected nations. …”
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Long-term antibiotic resistance surveillance of gram-negative pathogens suggests that temporal trends can be used as a resistance warning system
Published 2002“…The analysis of resistance levels and antibiotic consumption in the present study suggests different mechanisms for the increased resistance. The significant trend of increased resistance to antibiotics over time constitutes an important warning system.…”
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Trends in prescribing and outcomes in obese versus non-obese patients receiving rivaroxaban therapy: an observational study using real-world data
Published 2023“…Within BMI categories, a similar increasing trend was observed in underweight, normal, and overweight patients, while from 2018 to 2020, there was a decreasing trend in rivaroxaban prescribing in all obese classes. …”
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Myeloid Cells in Circulation and Tumor Microenvironment of Colorectal Cancer Patients with Early and Advanced Disease Stages
Published 2020“…Notably, patients with advanced disease stages showed significantly higher levels of GMCs compared to early stages in whole blood, but PBMCs and tumor-infiltrating myeloid cells did not show any significant differences. …”
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The effect of Dopamine Agonists on patients with advanced Parkinson's disease subjected to subthalamic deep brain stimulation. (c2000)
Published 2000“…Striatal dopamine concentration gets significantly reduced, and clinical symptoms, especially the motor handicap, prevail. …”
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Inland Treatment of the Brine Generated from Reverse Osmosis Advanced Membrane Wastewater Treatment Plant Using Epuvalisation System
Published 2013“…Plant growth parameters (plant height, fresh and dry weight) showed no significant difference between fresh water and brine treatments. …”
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Mental health and psychotropic medication trends during the COVID-19 pandemic in a middle eastern population: A systematic analysis of electronic medical records from Qatar
Published 2025“…ResultsA significant increase of 56.6 % in MHS outpatient visits was observed in 2022 compared to pre-pandemic levels, indicating heightened utilization of mental health services. …”
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Rising mortality related to cardiovascular disease and prostate cancer amongst older men across the United States
Published 2024“…</p><h3>Conclusion</h3><p dir="ltr">After decreasing death rates associated with CVD and PCa from 1999 to 2015, a reversal in the trend was observed from 2015 to 2019. Addressing this increase in death rates, especially among the vulnerable population, requires focused attention and targeted strategies to implement necessary safeguards in the upcoming years.…”