Search alternatives:
advances » advanced (Expand Search)
include » includes (Expand Search), included (Expand Search)
decrease » increase (Expand Search)
advances » advanced (Expand Search)
include » includes (Expand Search), included (Expand Search)
decrease » increase (Expand Search)
-
1
A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
-
2
Treating Cancers Using Nature’s Medicine: Significance and Challenges
Published 2021“…In recent decades, the emphasis on identifying therapeutic plant-based active principles led to significant advancements in the identification and use of natural compounds to treat various diseases (Figure 1) [2,3]. …”
-
3
Identifying and Assessing the Significance of Digital Twin Enablers in the Construction Industry
Published 2025Get full text
doctoralThesis -
4
-
5
The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
-
6
-
7
-
8
-
9
-
10
-
11
Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”
-
12
Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …”
-
13
Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
-
14
-
15
Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…”
Get full text
Get full text
Get full text
article -
16
-
17
-
18
Advancing Sustainable Energy Transition Through Green Hydrogen Valleys
Published 2025“…This review offers a comprehensive analysis of current scientific literature and recent advancements in GHV implementation, focusing on critical areas including electrolysis technology, material compatibility, hydrogen transportation, and economic feasibility. …”
-
19
-
20
Transforming Agricultural Food Waste Into Bioplastics: Methods, Potential, and Technological Advances
Published 2025“…<p dir="ltr">The improper disposal of agricultural food waste (AFW) and its associated plastic packaging significantly exacerbates environmental degradation, including pollution, greenhouse gas emissions, and loss of valuable resources, while imposing substantial economic burdens. …”