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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Agent-Based Reactive Geographic Routing Protocol for Internet of Vehicles
Published 2023“…In this paper, we first propose a novel lightweight location service that permits to discover all the geographical paths between two vehicles based on smart mobile agents. Second, we proposed ARGENT an Agent-Based Reactive Geographic Routing Protocol that couples the routing process with the novel lightweight location service. …”
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ARDENT: A Proactive Agent-Based Routing Protocol for Internet of Vehicles
Published 2023“…Then, we present an Agent-Based Proactive Geographic Routing Protocol called ARDENT to route data packets with reduced delay and higher delivery ratio. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Oral contraceptive pills and possible adverse effects
Published 2014“…Since their introduction to the market, there have been significant changes in the drug content and formulations of these products, in part to decrease the risk of adverse effects. …”
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Competition vs cooperation: An agent based model for sustainable tomatoes’ import system
Published 2024“…This paper suggests an Agent-based model-based framework that simulates the behavior and tracks the economic and environmental performances of the tomato supply system in the State of Qatar. …”
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The Impact of a Computerized Potassium Alert on Adverse Drug Events and Pharmacists' Interventions
Published 2010“…Conclusions: Implementation of a computerized pharmacy alert resulted in a statistically significant decrease in adverse drug events related to hyperkalemia in our institution. …”
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Studying Dynamics of Multi-Agent Learning in Networks
Published 2012“…Observations post to each case study have been made and key results have been formulated based on them. The result of the study showed that different parameters used in a network for example, (size of the network, time and interaction period between agents) have significant effect on the behavior of the artificial network. …”
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Dual-labeled trastuzumab-based imaging agent for the detection of human epidermal growth factor receptor 2 overexpression in breast cancer
Published 2007“…The tumor-to-muscle ratio decreased in mice pretreated with trastuzumab and in mice injected with IRDye 800CW and (111In-DTPA)p-IgG-(IRDye800)q. …”
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A Testing Framework for Blockchain-Based Energy Trade Microgrids Applications
Published 2024“…This study suggests executing such a testing within a framework that integrates a Geographic Information System (GIS) environment with an Agent-Based Modeling (ABM) simulation platform. The application of this testing framework to a case study of solar Photovoltaic (PV) energy trade among household peers in in Doha, Qatar, shows how the integration of the GIS environment offers a detailed analysis of transactions in local housing community markets. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Evaluation of light-activated Ru(II) prodrugs and their photoproducts as potential anti-cancer agents
Published 2020“…All complexes reduced significantly tumor growth 3 weeks post treatment when compared to non-treated mice. …”
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masterThesis
