Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways by Hadeel, Kheraldine

“…HER2-positive breast cancer is one of its most challenging subtypes, forming around 15–25% of the total cases. …”
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Neratinib and metformin: A novel therapeutic approach against HER2-Positive Breast Cancer by Kheraldine, Hadeel

“…BackgroundHER2-positive breast cancer (BC) is highly aggressive with a poor prognosis. …”
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HER2-positive apocrine carcinoma of the breast: a population-based analysis of treatment and outcome by Faruk Skenderi (6616190)

“…HER2+/APO tumors tend to have a less aggressive phenotype and a more favorable outcome despite a markedly lower ER/PR positivity.</p><h2>Other Information</h2> <p> Published in: Breast Cancer Research and Treatment<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1007/s10549-022-06578-4" target="_blank">http://dx.doi.org/10.1007/s10549-022-06578-4</a></p>…”

Ratio between positive lymph nodes and total excised axillary lymph nodes as an independent prognostic factor for overall survival in patients with nonmetastatic lymph node-positiv... by Dimassi, Hani

“…The status of the axillary lymph nodes in nonmetastatic lymph node-positive breast cancer (BC) patients remains the single most important determinant of overall survival (OS). …”
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Gene Expression and miRNAs Profiling: Function and Regulation in Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer by Rasha M. Sareyeldin (18131371)

“…Despite the anti-HER2 and cytotoxic chemotherapy, HER2 subtype is an aggressive disease with significant mortality. Recent advances in molecular biology techniques, including gene expression profiling, proteomics, and microRNA analysis, have been extensively used to explore the underlying mechanisms behind human breast carcinogenesis and metastasis including HER2-positive breast cancer, paving the way for developing new targeted therapies. …”

Targeting HER2-positive breast cancer cells by a combination of dasatinib and BMS-202: Insight into the molecular pathways by Hadeel Kheraldine (14231609)

“…</p><h3>Conclusion</h3><p dir="ltr">Our findings implicate that a combination of DA and BMS-202 could have a significant impact on the management of HER2-positive breast cancer.…”

Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways by Hadeel Kheraldine (14231609)

“…<p>HER2-positive breast cancer is one of its most challenging subtypes, forming around 15–25% of the total cases. …”

Breast cancer screening in Lebanon: Understanding knowledge, attitudes and barriers by Elias-Rizk, Tamina

“…Background Breast cancer (BC) has been increasing in both prevalence and incidence in Lebanon. …”
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Evaluation of Estrone Liposomes using Microfluidics for Breast Cancer Therapy by Al Bostami, Rouba D.

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Discrimination of breast cancer from benign tumours using Raman spectroscopy by Fiona M. Lyng (2189614)

“…Breast cancer is diagnosed by histopathological examination of breast biopsy material but this is subjective and relies on morphological changes in the tissue. …”

Ultrasound triggered release of Trastuzumab-conjugated immunoliposomes targeting breast cancer by Ahmed, Amal Elsadig Elamir

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Correction: Discrimination of breast cancer from benign tumours using Raman spectroscopy by Fiona M. Lyng (2189614)

“…<p dir="ltr">Correction to: Discrimination of breast cancer from benign tumours using Raman spectroscopy. …”

Diagnostic test accuracy of AI-assisted mammography for breast imaging: a narrative review by Daksh Dave (17949239)

“…The motivation for this research lies in addressing the need for enhanced diagnostic tools in breast cancer screening, where early detection can significantly impact patient outcomes. …”

Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma by Peter Kubatka (11008854)

“…In conclusion, sumac demonstrated significant oncostatic activities in rodent models of breast carcinoma that were validated by mechanistic studies in vivo and in vitro.…”

Imaging Patterns in Breast Cancer for Women Under 40 Years: A Descriptive Cohort Study by Amal A. Alhaidary (21633410)

“…Out of the 73 patients who underwent genetic tests, 32.9% tested positive for gene mutations. No statistically significant correlation was found between specific age groups and breast composition (<i>P</i> = 0.216), specific mammogram abnormalities such as masses (<i>P</i> = 0.262), or microcalcifications (<i>P</i>= 0.421). …”

Ultrasonically Triggered Release of Folic Acid-Conjugated Liposomes for Breast Cancer Therapy Within Microfluidic Devices by AlHazaimeh, Taima Khair Alla

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Systems biology analysis reveals NFAT5 as a novel biomarker and master regulator of inflammatory breast cancer by Andrea Remo (447375)

“…The expression pattern of the most significant MRs was then evaluated by immunohistochemistry (IHC) in two independent cohorts of IBCs (n = 39) and nIBCs (n = 82) and normal breast tissues (n = 15) spotted on tissue microarrays. …”

CXCR7 signaling promotes breast cancer survival in response to mesenchymal stromal stem cell-derived factors by Mashael Al-toub (3563303)

“…Interestingly, significant positive correlation between CXCR7 and CXCL12 gene expression (Pearson = 0.3, p = 2.0 × 10–16) was observed in breast cancer patients, suggesting a biological role for the CXCR7/CXCL12 genetic circuit in breast cancer biology. …”

Breast Cancer Screening Practices in a Tertiary Care Center in the State of Qatar: A Cross-Sectional Survey by Jessiya Veliyankodan Parambil (16518660)

“…While the attitude towards breast cancer screening is positive, the overall compliance with the national recommendations is sub-optimal. …”

Prognostic values of the mRNA expression of natural killer receptor ligands and their association with clinicopathological features in breast cancer patients by Ali Abouelghar (14152773)

“…In addition, the favorable prognostic influence of NK-activating ligands’ upregulation, as a whole, was mainly significantly associated with HER2-positive and basal-like subtypes, lymph node positive phenotype, and high-grade tumors.…”