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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…To assess the effect of kefir on cancer metastasis, wound‑healing and time‑lapse movies, in addition to collagen‑based invasion assay, were used. The results show that cell‑free fractions of kefir exhibit an anti‑proliferative effect on Caco‑2 and HT‑29 cells. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
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RL-Based Adaptive UAV Swarm Formation and Clustering for Secure 6G Wireless Communications in Dynamic Dense Environments
Published 2024“…Our work introduces an adaptive UAV swarm formation and dynamic device clustering technique designed for efficient anti-jamming in dynamic multi-user clusters threatened by unknown jammers during critical public events. …”
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Studies on anti-colon cancer potential of nanoformulations of curcumin and succinylated curcumin in mannosylated chitosan
Published 2023“…Here, we aim to assess the anti-CRC activity of these two nanoformulations. …”
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Studies on anti-colon cancer potential of nanoformulations of curcumin and succinylated curcumin in mannosylated chitosan
Published 2023“…Here, we aim to assess the anti-CRC activity of these two nanoformulations. …”
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Evaluation of light-activated Ru(II) prodrugs and their photoproducts as potential anti-cancer agents
Published 2020“…All complexes reduced significantly tumor growth 3 weeks post treatment when compared to non-treated mice. …”
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
Published 2025“…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…”
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Novel Platinum II and Platinum IV Complexes Exhibit An Anti-Neoplastic Potential Against A549 Cancer Cell Line
Published 2021“…The present study aims to test the anti-neoplastic activity of novel Pt II and Pt IV complexes against A549 lung cancer cells and elucidate the mechanism of action involved. …”
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Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through...
Published 2021“…Results The method of measuring reflectivity is good to excellent reliability for all regions of interest except the fourth. The mean reflectivity of the choriocapillaris and Sattler’s layer in amblyopic eyes were significantly lower than in healthy eyes (p = 0.003 and p = 0.008 respectively). …”
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Snake venom in conjugation with silica nanoparticles: an emerging cancer therapy
Published 2025“…Snake venom, consisting of a complex mixture of bioactive proteins and peptides, has demonstrated significant anti-cancer effects such as cytotoxicity, angiogenesis inhibition, and apoptosis induction. …”