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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Exploring the dynamics of algae-associated microbiome during the scale-up process of Tetraselmis sp. microalgae: A metagenomics approach
Published 2023“…Microbial profiling of each successive stage revealed lower abundance of eukaryotic organisms, whereas bacterial abundance increased notably resulting in a significant decrease in Tetraselmis sp. abundance. …”
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Exploring the dynamics of algae-associated microbiome during the scale-up process of Tetraselmis sp. microalgae: A metagenomics approach
Published 2024“…Microbial profiling of each successive stage revealed lower abundance of eukaryotic organisms, whereas bacterial abundance increased notably resulting in a significant decrease in Tetraselmis sp. abundance. …”
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Current trends and future orientation in diagnosing lung pathologies: A systematic survey
Published 2025“…These VOCs can aid in the diagnosis of lung pathologies such as pneumonia. The CV processing method involves the application of advanced imaging techniques and machine learning algorithms to scrutinize and diagnose lung pathologies and ventilator-associated pneumonia (VAP). …”
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A Methodology of Rule Discovery from Large-scale Multi-tier Noisy Educational Data
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Staff Development: A Study Into The Significance of Staff Professional Development Programs for Educators and Students Achievement
Published 2011“…Several authors/ researchers have made an attempt to touch upon the different dimensions associated with PD programs. This dissertation attempts to study the significance of staff professional development for educators and how it can affect students’ achievement. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Protocadherin of the liver, kidney and colon associates with detergent-resistant membranes during cellular differentiation
Published 2010“…This association occurs concomitant with alterations in the glycosylation pattern. …”
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Hypospadias-associated penile curvature assessment and management: A global survey of current practice
Published 2024“…<h3>Introduction</h3><p dir="ltr">Our goal was to assess how surgical management of hypospadias-associated penile curvature (HAPC) varies across continents, focusing on factors that influence assessment and decision-making.…”
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Epigenetics meets proteomics in an epigenome-wide association study with circulating blood plasma protein traits
Published 2020“…We identify 98 CpG-protein associations (pQTMs) at a stringent Bonferroni level of significance. …”
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A comparative economic analysis of conventional and modified Solvay processes vs. solar ponds for brine management
Published 2025“…Overall, modified Solvay process not only generates profit but also simultaneously mitigates CO₂ emissions and reduces reject brine salinity significantly compared to Conventional Solvay. …”
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Parkinson’s disease and schizophrenia interactomes contain temporally distinct gene clusters underlying comorbid mechanisms and unique disease processes
Published 2024“…<p dir="ltr">Genome-wide association studies suggest significant overlaps in Parkinson’s disease (PD) and schizophrenia (SZ) risks, but the underlying mechanisms remain elusive. …”