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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Policy Brief: Addressing Barriers and Empowering Entrepreneurs in Lebanon.
Published 2025“…This policy brief examines the key factors influencing entrepreneurial success in Lebanon, focusing on gender dynamics, socio-cultural barriers, and systemic challenges. Entrepreneurship plays a critical role in Lebanon’s economic growth, innovation, and job creation, yet local entrepreneurs face significant obstacles. …”
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Barriers of Adopting Artificial Intelligence Tools in Engineering Construction Projects
Published 2023“…Engineering construction projects using AI technologies create obstacles. Barriers prevent AI integration in construction. Insufficient knowledge and understanding of AI, data management and integration issues, legal and regulatory hurdles, financial considerations, reluctance to change, and interoperability issues all hinder AI system adoption and implementation. …”
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Breast cancer screening in Lebanon: Understanding knowledge, attitudes and barriers
Published 2024“…Furthermore, 38.5 % encountered obstacles to mammography screening. Education significantly affected BC knowledge. Interestingly, increased knowledge of BC reduced barriers to mammographic screening. …”
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The Environmental Barriers to Active School Travel Among Private School Students in Dubai
Published 2021“…Among built environment features, street connectivity and traffic calming measures are significant factors. Since most of the private school students in Dubai are living beyond the walking distance threshold, it may be concluded that distance between home and school is the main barrier to AST.…”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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Policy Brief on Entrepreneurship in Lebanon Unlocking Potentials: Addressing Barriers and Empowering Entrepreneurs in Lebanon
Published 2024“…The socio-cultural context presents unique barriers for women entrepreneurs, who face gender norms and structural inequalities. …”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
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Predictors, barriers, and facilitators to refugee women’s employment and economic inclusion: A mixed methods systematic review
Published 2024“…The qualitative synthesis uncovers three key themes: the meaning and significance of employment; barriers to employment; and facilitators and coping for employment. …”
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Policy Brief on Entrepreneurship in UAE Fostering Inclusive Growth for Nascent Entrepreneurs in the UAE: Addressing Gender and Cultural Barriers
Published 2024“…This paper highlights the significant progress the UAE has made in developing its entrepreneurial landscape while emphasizing persistent challenges faced by women. …”
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Attitudes, motivators, and barriers toward influenza vaccination for children: a study from a conflict-ridden country
Published 2024“…<h3>Background</h3><p dir="ltr">Despite the increased recommendations for influenza vaccination, particularly among high-risk groups such as young children, Yemen lacks an influenza vaccination program, and the influenza vaccine is not included in the national immunization regime. …”
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12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase
Published 2013“…ROS generation and NOX2 expression were also measured in mice retinas. 12- and 15- HETE significantly increased permeability and reduced TER and ZO-1expression in REC. …”
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
Published 2025“…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…”
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Compliance and barriers to the use of infection prevention and control measures among health care workers during COVID‐19 pandemic in Qatar: A national survey
Published 2021“…Participants reported a significant increase in the median self-rated compliance scores during the pandemic compared with before it (<em>p</em> < .001). …”
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Developing a Sustainable Procurement Action Plan for Public Sector in Ajman
Published 2011“…Depletion of natural resources, affecting biodiversity and increasing poverty are common challenges faced by many communities all around the world. …”
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