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Assessing uncertainty in image-based monitoring: addressing false positives, false negatives, and base rate bias in structural health evaluation
Published 2025“…However, its reliability is impacted by challenges such as false positives, false negatives, and environmental variability, particularly in low base rate damage scenarios. The Base Rate Bias plays a significant role, as low probabilities of actual damage often lead to misinterpretation of positive results. …”
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Influence of Cognitive Bias on Decision Making in Mega Projects
Published 2020“…The main reasons for cost overrun have been clustered into three groups namely technical, optimism bias and strategic misrepresentation. Since mega projects are increasing in size and number, and their poor performance has been consistent despite various proposals suggested based on project management best practices that have mainly focused on the technical element of implementing mega projects, the performance in mega projects has not improved prompting this study to focus on optimism bias and strategic misrepresentation where if optimism is exceeded, it is termed as over optimism and leads to cost overrun due to significant underestimation of costs. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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The Influence of Cognitive Bias Attributes on Decision-making Style of the Project Manager: The Moderating Role of Narcissistic and Voice Behaviour
Published 2022“…The results indicated that: 1) CBA influences the decision-making style of project managers, 2) the relationship between CBA and the experiential decision-making style of the project manager is significant, whereas the rational decision-making style of the project managers is less affected by CBA, 3) using the experiential style to make a decision under uncertain events has a relatively negative influence on the success of projects as it is connected to CBA, 4) using the rational style to make a decision under uncertain events has a relatively positive influence on the success of the projects as it is less connected to CBA, 5) voice behaviour negatively moderates the relationship between cognitive bias and the decision-making style of project managers; however, the relationship was weak, and 6) NB does not moderate the relationship between CBA and the DM style. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Deep learning-based modeling of land use/land cover changes impact on land surface temperature in Greater Amman Municipality, Jordan (1980–2030)
Published 2024“…However, agricultural areas decreased from 152.13 km<sup>2</sup> (18.5%) in 1980 to 140.38 km<sup>2</sup> (17%) in 2023, while barren lands decreased from 54.44 km<sup>2</sup> (6.6%) in 1980 to 34.71 km<sup>2</sup> (4.22%) in 2023. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…”
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Site-Adaptation of Modeled Solar Radiation Data: The SiteAdapt Procedure
Published 2020“…It was tested at nine sites in a wide range of latitudes and climates, resulting in significant improvements of statistical indicators of dispersion, distribution similarity and overall performance: relative bias is reduced on average from −1.8% and −2.3% to 0.1% and 0.3% for GHI and DNI, respectively; relative root mean square deviation is reduced on average from 17.9% and 34.9% to 14.6% and 29.8% for GHI and DNI, respectively; the distribution similarity is also improved after the site-adaptation (KSI is 3.5 and 3.9 times lower for GHI and DNI at hourly scale, respectively). …”
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published 2021“…VISTA and AHR levels were assessed by qPCR, Western blot, immunofluorescence microscope, flow cytometry, and immunohistochemistry. Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …”
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Follow up and comparative assessment of IgG, IgA, and neutralizing antibody responses to SARS-CoV-2 between mRNA-vaccinated naïve and unvaccinated naturally infected individuals ov...
Published 2023“…At the 7th month, there was a significant decline in antibody responses among VN individuals, but not NI individuals, with a minimum decrease of 3.7-fold (p < 0.001). …”
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