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Showing 1 - 20 results of 170 for search '(( significant bias based ) OR ( significant ((genes decrease) OR (mean decrease)) ))', query time: 0.13s Refine Results
  1. 1

    Assessing uncertainty in image-based monitoring: addressing false positives, false negatives, and base rate bias in structural health evaluation by Vagelis Plevris (14158863)

    Published 2025
    “…However, its reliability is impacted by challenges such as false positives, false negatives, and environmental variability, particularly in low base rate damage scenarios. The Base Rate Bias plays a significant role, as low probabilities of actual damage often lead to misinterpretation of positive results. …”
  2. 2

    Influence of Cognitive Bias on Decision Making in Mega Projects by ALNUAIMI, WALEED

    Published 2020
    “…The main reasons for cost overrun have been clustered into three groups namely technical, optimism bias and strategic misrepresentation. Since mega projects are increasing in size and number, and their poor performance has been consistent despite various proposals suggested based on project management best practices that have mainly focused on the technical element of implementing mega projects, the performance in mega projects has not improved prompting this study to focus on optimism bias and strategic misrepresentation where if optimism is exceeded, it is termed as over optimism and leads to cost overrun due to significant underestimation of costs. …”
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    The Influence of Cognitive Bias Attributes on Decision-making Style of the Project Manager: The Moderating Role of Narcissistic and Voice Behaviour by OBEIDAT, OMAR SALEM

    Published 2022
    “…The results indicated that: 1) CBA influences the decision-making style of project managers, 2) the relationship between CBA and the experiential decision-making style of the project manager is significant, whereas the rational decision-making style of the project managers is less affected by CBA, 3) using the experiential style to make a decision under uncertain events has a relatively negative influence on the success of projects as it is connected to CBA, 4) using the rational style to make a decision under uncertain events has a relatively positive influence on the success of the projects as it is less connected to CBA, 5) voice behaviour negatively moderates the relationship between cognitive bias and the decision-making style of project managers; however, the relationship was weak, and 6) NB does not moderate the relationship between CBA and the DM style. …”
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  5. 5

    A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

    Published 2024
    “…<p dir="ltr">NanoLuc (NLuc) <u>luciferase</u> has found extensive application in designing a range of <u>biologica</u><u>l</u><u> assays,</u> including <u>gene expression analysis</u>, protein-protein interaction, and protein conformational changes due to its enhanced brightness and small size. …”
  6. 6

    Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

    Published 2019
    “…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
  7. 7

    Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion by Khoury, Nathalie

    Published 2014
    “…The expression of certain genes involved in proliferation and apoptosis was measured using reverse transcriptase‑polymerase chain reaction (RT‑PCR) and western blotting. …”
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  8. 8

    Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk by Merhi, Mahmoud

    Published 2015
    “…Moreover, a significant smoking-gene interaction is determined with CYP1A1 MspI polymorphism rs4646903 and is associated with a decreased risk of CAD in current smokers (OR 0.52137). …”
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  9. 9

    Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications by Jingxuan Shan (4711089)

    Published 2019
    “…We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …”
  10. 10

    Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through... by Masri, Oussama Samer

    Published 2021
    “…Results The method of measuring reflectivity is good to excellent reliability for all regions of interest except the fourth. The mean reflectivity of the choriocapillaris and Sattler’s layer in amblyopic eyes were significantly lower than in healthy eyes (p = 0.003 and p = 0.008 respectively). …”
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  11. 11

    Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients by Esraa K. Al-Amleh (16023071)

    Published 2022
    “…Platelet counts, on the other hand, dramatically decreased in both IM and (HU + IM).</p><h3>Conclusion</h3><p dir="ltr">Because the studied genes (BCL2, PP2A, CIP2A, and WT1) are participating in cell proliferation and death, the findings show that the examined genes are significant to understand the efficacy of various therapies. …”
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    Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes by Maryam Aghadi (17128819)

    Published 2022
    “…Lack of FOXA2 resulted in significant alterations in the expression of key developmental and functional genes in hepatic progenitors (HP) and mature hepatocytes (MH) as well as an increase in the expression of ER stress markers. …”
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    Site-Adaptation of Modeled Solar Radiation Data: The SiteAdapt Procedure by Carlos M. Fernández-Peruchena (18558904)

    Published 2020
    “…It was tested at nine sites in a wide range of latitudes and climates, resulting in significant improvements of statistical indicators of dispersion, distribution similarity and overall performance: relative bias is reduced on average from −1.8% and −2.3% to 0.1% and 0.3% for GHI and DNI, respectively; relative root mean square deviation is reduced on average from 17.9% and 34.9% to 14.6% and 29.8% for GHI and DNI, respectively; the distribution similarity is also improved after the site-adaptation (KSI is 3.5 and 3.9 times lower for GHI and DNI at hourly scale, respectively). …”
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    Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 by Olfa Khalifa (10914452)

    Published 2023
    “…</p> <p>Results: Treatment with 200nM Ex-4 for 3h decreased the OA-induced lipid buildup significantly (p<0.05). …”
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    As you sow, so shall you reap: Assessing drivers of socially responsible investment attitude and intention by Aashish Garg (17380339)

    Published 2022
    “…The research hypotheses were tested using covariance-based structural equation modelling (SEM). The findings suggest that investors' values (collectivism and biospheric values), biases (social responsibility bias and reliance on expert bias), and perceived performance of SRI contribute positively to the intentions towards SRI. …”
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    Evaluating the impact of a brief Health at Every Size-informed health promotion activity on body positivity and internalized weight-based oppression by Lily, O’Hara

    Published 2021
    “…Weight-based oppression, including negative attitudes about body weight, and harassment, stigma, and discrimination based on body weight, is a widespread phenomenon that leads to considerable distress and poor health and wellbeing outcomes. …”
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  19. 19

    Application of bipolar membrane (BPM)-based technology to green energy and environmental sustainability by Sajna M.S. (22302991)

    Published 2025
    “…We examine the operational mechanisms of BPMs under forward and reverse bias, focusing on their integration into applications such as <u>water electrolysis </u>for<u> hydrogen generation</u>, fuel cells, <u>redox flow batteries</u>, and CO<sub>2</sub> electrolysis. …”
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    Robotic-assisted versus conventional total knee arthroplasty: a systematic review and meta-analysis of randomized controlled trials by Reda Alrajeb (17773221)

    Published 2023
    “…</p><h3>Results</h3><p dir="ltr">Our search returned seven RCTs suitable for our analysis, which included a total of 1942 knees; 974 of these knees were implanted using robotic arms while the remaining 968 utilized jig-based knee systems. Our findings indicated that robotic knees had significantly better post-operative anatomical (OR − 0.82; 95% CI, − 1.027 to − 0.58, p value < 0.00001) and mechanical restoration (OR − 0.95; 95% CI, − 1.49 to − 0.41, p value < 0.0006). …”