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Showing 1 - 20 results of 124 for search '(( significant binding based ) OR ( significant ((i.e decrease) OR (mean decrease)) ))', query time: 0.11s Refine Results
  1. 1

    Coevolving residues distant from the ligand binding site are involved in GAF domain function by Wesam S. Ahmed (10170053)

    Published 2025
    “…<p dir="ltr">Ligand binding to GAF domains regulates the activity of associated catalytic domains in various proteins, such as the cGMP-hydrolyzing catalytic domain of phosphodiesterase 5 (PDE5) activated by cGMP binding to GAFa domain. …”
  2. 2

    A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

    Published 2024
    “…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. …”
  3. 3

    Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model by Sahar Isa Da’as (18288880)

    Published 2022
    “…Furthermore, heart transcriptome profiling showed a significant downregulation of the actin-filament-based process, indicating an impaired actin cytoskeleton organization as the main dysregulating factor associated with the early ventricular cardiac hypertrophy in the zebrafish mypbc3 HCM model.…”
  4. 4

    Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through... by Masri, Oussama Samer

    Published 2021
    “…Results The method of measuring reflectivity is good to excellent reliability for all regions of interest except the fourth. The mean reflectivity of the choriocapillaris and Sattler’s layer in amblyopic eyes were significantly lower than in healthy eyes (p = 0.003 and p = 0.008 respectively). …”
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  5. 5

    Nanoparticle enrichment mass-spectrometry proteomics identifies protein-altering variants for precise pQTL mapping by Karsten Suhre (67967)

    Published 2024
    “…Most previous work has been conducted using affinity-based proteomics approaches. These technologies face challenges, such as uncertainty regarding target identity, non-specific binding, and handling of variants that affect epitope affinity binding. …”
  6. 6

    Efficient mechanochemical synthesis of new fluorinated Schiff bases: a solvent-free, alternative to conventional method with mercury adsorption properties by Mirza T. Baig (14152407)

    Published 2025
    “…The synthesized fluorinated Schiff bases are evaluated for their adsorption capacity and efficiency in mercury removal and compared to assess their performance, demonstrating that ball milling produced compounds with comparable physical attributes to those produced via traditional solvent-based procedures. …”
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    Computational identification of genetic subnetwork modules associated with maize defense response to Fusarium verticillioides by Mansuck Kim (19570903)

    Published 2015
    “…The other two predicted modules were indirectly involved in the defense response, where the most significant GO terms associated with these modules were GO:0046914 (transition metal ion binding) and GO:0046686 (response to cadmium ion). …”
  9. 9

    SARS‐CoV‐2 infection triggers more potent antibody‐dependent cellular cytotoxicity (ADCC) responses than mRNA‐, vector‐, and inactivated virus‐based COVID‐19 vaccines by Hadeel T. Zedan (12535521)

    Published 2024
    “…Although post‐mRNA vaccination BTI elicited high levels of binding and NAbs, ADCC activity was significantly reduced. …”
  10. 10

    Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension by Thiruveni Ramkumar (17075051)

    Published 2023
    “…On the other hand, neonates of hypertensive mothers administered with methyldopa showed a significant decrease of initial blood glucose reading.…”
  11. 11

    Rescue cerclage by Khoury, Alfred

    Published 2006
    “…Advanced dilation of 3 cm and/or prolapsed membranes (n = 18) did not decrease the likelihood of reaching 28 weeks. Mean gestational age at delivery for this subset of patients was 30.7 ± 7.2 weeks. …”
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  12. 12

    Food safety knowledge attitude and practices of oncology nurses, in Lebanese hospitals by Angy, Mallah

    Published 2023
    “…Knowledge scores were higher among nurses holding a graduate degree (mean = 85; p < 0.05), and those who attended a training course (mean = 79; p < 0.05). …”
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  13. 13

    Transfer function analysis between arterial pressure and renal sympathetic nerve activity at cardiac pacing frequencies in the rat by Kanbar, Roy

    Published 2007
    “…Cardiac pacing slightly increased mean AP (0.8 ± 0.2 mmHg/Hz) and decreased pulse pressure (−3.6 ± 0.3 mmHg/Hz) while leaving the mean level of RSNA essentially unaltered (P = 0.680, repeated-measures ANOVA). …”
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  14. 14

    Structure-guided engineering and molecular simulations to design a potent monoclonal antibody to target aP2 antigen for adaptive immune response instigation against type 2 diabetes by Abbas Khan (5141000)

    Published 2024
    “…This approach involved screening a mutational landscape comprising 57 mutants to identify modifications that yield significant enhancements in binding efficacy and stability.…”
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    Food safety knowledge attitude and practices of oncology nurses, in Lebanese hospitals by Angy Mallah (17831954)

    Published 2023
    “…Knowledge scores were higher among nurses holding a graduate degree (mean = 85; p < 0.05), and those who attended a training course (mean = 79; p < 0.05). …”
  18. 18

    Investigating the impact of remittance outflows and oil price on economic growth in Gulf Cooperation Council countries by Mouyad Alsamara (17823668)

    Published 2023
    “…These findings have significant implications for labor markets and nationalization policies in the GCC countries.…”
  19. 19

    Investigating the impact of remittance outflows and oil price on economic growth in Gulf Cooperation Council countries by Mouyad, Alsamara

    Published 2023
    “…These findings have significant implications for labor markets and nationalization policies in the GCC countries.…”
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  20. 20

    Oxygen targets following cardiac arrest: A meta-analysis of randomized controlled trials by Huzaifa Ahmad Cheema (16328980)

    Published 2023
    “…</p> <h3>Conclusions</h3> <p>Conservative oxygen therapy did not decrease mortality, improve neurologic recovery, or decrease ICU LOS as compared to a liberal oxygen regimen. …”