Showing 1 - 20 results of 274 for search '(( significant burden increase ) OR ( significant clinical decrease ))', query time: 0.14s Refine Results
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    Trends of the Dementia Burden in South Asia: An Analysis of 2021 Global Burden of Disease Study by Shubham Chauhan (21334742)

    Published 2025
    “…While prevalence rates experienced a minor decline, Disability‐Adjusted Life Years (DALYs) rose from 272.02 to 308.27 per 100,000, reflecting an increasing burden of the disease. Notably, Nepal significantly reduced its incidence rates, while Pakistan saw an increase in mortality rates. …”
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    Pill-burden and its association with treatment burden among patients with advanced stages of chronic kidney disease by Asmaa, Al-mansouri

    Published 2023
    “…Overall, patients who had high pill-burden (≥112 pills/week) had significantly higher perceived treatment burden compared to low pill-burden patients (<112 pills/week) [47(36.2) vs. 38.5(36.7); p = 0.0085]. …”
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    Prostate cancer burden in South Asia: A systematic analysis of global burden of disease data (1990–2021) by Vijay Kumar (377076)

    Published 2024
    “…</p><h3>Results</h3><p dir="ltr">The prostate cancer ASIR, ASPR, and ASDR significantly increased from 1990 to 2021, particularly among individuals aged 60–65 years. …”
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    Burden of Transport-Related Injuries in the Eastern Mediterranean Region: A Systematic Analysis for the Global Burden of Disease Study 2017 by Saeid Safiri (3713035)

    Published 2021
    “…</p><h3>Results</h3><p dir="ltr">In 2017, there were 5.5 million (UI 4.9–6.2) transport-related incident cases in the EMR – a substantial increase from 1990 (2.8 million; UI 2.5–3.1). The age-standardized incidence rate for the EMR in 2017 was 787 (UI 705.5–876.2) per 100000,which has not changed significantly since 1990 (-0.9%; UI -4.7 to 3). …”
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    Temporal patterns of cancer burden in Asia, 1990–2019: a systematic examination for the Global Burden of Disease 2019 study by Rajesh, Sharma

    Published 2024
    “…Cancer DALYs due to ambient PM pollution, high body mass index and fasting plasma glucose has increased most notably between 1990 and 2019. InterpretationWith growing incidence, cancer has become more significant public health threat in Asia, demanding urgent policy attention and guidance. …”
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    Assessment of treatment burden and its impact on quality of life in dialysis-dependent and pre-dialysis chronic kidney disease patients by Asmaa Al-mansouri (16931739)

    Published 2021
    “…HD patients experienced significantly higher burden of treatment and lower HR-QOL compared to pre-dialysis patients and that HR-QOL declines as treatment burden increases. …”
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    Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019 by Gregory A. Roth (6302315)

    Published 2020
    “…The global trends for disability-adjusted life years (DALYs) and years of life lost also increased significantly, and years lived with disability doubled from 17.7 million (95% UI: 12.9 to 22.5 million) to 34.4 million (95% UI:24.9 to 43.6 million) over that period. …”
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    Burden and disease pathogenesis of influenza and other respiratory viruses in diabetic patients by Swapna Thomas (17337925)

    Published 2022
    “…<p dir="ltr">Over the past two decades, diabetes mellitus (DM) has been receiving increasing attention among autoimmune diseases. The prevalence of type 1 and <u>type</u><u> </u><u>2 diabetes</u> has increased rapidly and has become one of the leading causes of death worldwide. …”
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    Global, regional and national burden of bladder cancer and its attributable risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of... by Saeid Safiri (3713035)

    Published 2021
    “…</p><h3>Conclusions</h3><p dir="ltr">There was considerable variation in the burden of bladder cancer between countries during the period 1990–2019. …”
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    National-level and state-level prevalence of overweight and obesity among children, adolescents, and adults in the USA, 1990–2021, and forecasts up to 2050 by Marie, Ng

    Published 2024
    “…BackgroundOver the past several decades, the overweight and obesity epidemic in the USA has resulted in a significant health and economic burden. Understanding current trends and future trajectories at both national and state levels is crucial for assessing the success of existing interventions and informing future health policy changes. …”
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    Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

    Published 2022
    “…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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    Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis... by Marissa B Reitsma (8674341)

    Published 2021
    “…Although prevalence of smoking had decreased significantly since 1990 among both males (27·5% [26·5–28·5] reduction) and females (37·7% [35·4–39·9] reduction) aged 15 years and older, population growth has led to a significant increase in the total number of smokers from 0·99 billion (0·98–1·00) in 1990. …”
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    Effect of clinical hyperthyroidism and hypothyroidism on patent diabetes. 59 cases by Hirbli, K.

    Published 1983
    “…Fifty-nine patients with both clinical evidence of thyroid dysfunction and patent diabetes mellitus were investigated in our diabetology department. …”
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    Evidence and gaps in clinical outcomes of novel pharmacologic therapies for sickle cell disease: A systematic literature review highlighting insights from clinical trials and real-... by Mohamed Yassin (4166515)

    Published 2025
    “…The high discontinuation rate and results of the STAND trial led to a significant decrease in the use of crizanlizumab. The HOPE trial demonstrated a 51 % improvement in hemoglobin response and a reduction in hemolytic markers in patients treated with voxelotor. …”