Both decreasing interstructural space size and increasing total cover increase shrimp abundance on artificial structures deployed in a UAE seagrass bed by Bartholomew, Aaron

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L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression by Rached, Johnny

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Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Vijay Ganji (8710491)

The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... by Wesal Habbab (17346961)

“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”

A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”

Applications of bioconvection for tiny particles due to two concentric cylinders when role of Lorentz force is significant by Lei Zhang (38117)

Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”

Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion by Khoury, Nathalie

“…Results from RT‑PCR showed that kefir decreases the expression of transforming growth factor α (TGF‑α); and transforming growth factor‑β1 (TGF‑β1) in HT‑29 cells. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells by Shebaby, Wassim N.

“…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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Dynamic model scaling based on segmented tumor size for breast cancer detection by Younes Akbari (16303286)

“…The segmentation model, trained on a specialized dataset of breast cancer regions, identifies tumor regions in testing images from breast cancer detection datasets. …”

The identification of highly upregulated genes in claudin-low breast cancer through an integrative bioinformatics approach by Hatem, Zayed

“…This study aimed to identify upregulated genes and significant pathways involved in CLBC. The SUM159 cell line is derived from human CLBC tissue; the GSE50697 dataset contains three replicates of SUM159 cells treated with pBabe puro miR-203 and three replicates of control SUM159 cells (pBabe puro). …”
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Hybrid Model for Detection of Cervical Cancer Using Causal Analysis and Machine Learning Techniques by Umesh Kumar Lilhore (17727684)

“…This research proposed an efficient feature selection and prediction model for cervical cancer datasets using Boruta analysis and SVM method to deal with this challenge. …”

Ancestry-associated transcriptomic profiles of breast cancer in patients of African, Arab, and European ancestry by Jessica Roelands (7516439)

“…We applied a unique approach that combines the use of curated survival data from The Cancer Genome Atlas (TCGA) Pan-Cancer clinical data resource, improved single-nucleotide polymorphism-based inferred ancestry assignment, and a novel breast cancer subtype classification to interrogate the TCGA and a local Arab breast cancer dataset. …”

The identification of highly upregulated genes in claudin-low breast cancer through an integrative bioinformatics approach by Hatem Zayed (835448)

“…This study aimed to identify upregulated genes and significant pathways involved in CLBC. The SUM159 cell line is derived from human CLBC tissue; the GSE50697 dataset contains three replicates of SUM159 cells treated with pBabe puro miR-203 and three replicates of control SUM159 cells (pBabe puro). …”

The utility of a deep learning-based approach in Her-2/neu assessment in breast cancer by Saidul Kabir (15302407)

“…It is present in 15 to 20% of breast cancers and is clinically significant due to the availability of multiple anti-Her2 treatment options. …”

The utility of a deep learning-based approach in Her-2/neu assessment in breast cancer by Saidul, Kabir

“…It is present in 15 to 20% of breast cancers and is clinically significant due to the availability of multiple anti-Her2 treatment options. …”
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Immune-related 3-lncRNA signature with prognostic connotation in a multi-cancer setting by Shimaa Sherif (12862990)

“…</p><h3>Methods</h3><p dir="ltr">We developed a multi-step process to identify immune-related long non-coding RNA signatures with prognostic connotation in multiple TCGA solid cancer datasets.</p><h3>Results</h3><p dir="ltr">Using the breast cancer dataset as a discovery cohort we found 2988 differentially expressed lncRNAs between immune favorable and unfavorable tumors, as defined by the immunologic constant of rejection (ICR) gene signature. …”

A novel virtual patient approach for cross-patient multimodal fusion in enhanced breast cancer detection by Younes Akbari (16303286)

“…<p>Multimodal medical imaging combining conventional imaging modalities such as mammography, ultrasound, and histopathology has shown significant promise for improving breast cancer detection accuracy. …”

LSCS-Net: A lightweight skin cancer segmentation network with densely connected multi-rate atrous convolution by Sadia Din (18136919)

“…The generalization capabilities of LSCS-Net are testified by the excellent performance on breast cancer and thyroid nodule segmentation datasets. The empirical findings confirm that LSCS-net attains state-of-the-art results, as demonstrated by a significantly elevated Jaccard index.…”

Distinct genomic features across cytolytic subgroups in skin melanoma by Constantinos Roufas (4871131)

“…We found a broader pattern of chromothripsis across CYT-low tumors, where chromosomal regions harboring chromothriptic events, contained a higher number of cancer genes. SBS7a/b, SBS5 and SBS1 were the most prevalent mutational signatures across both cytolytic subgroups, but SBS1 differed significantly between them. …”