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Genome-Based Characterization of Bacterial Pathogens Causing Bloodstream Infection
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Causes of construction reworks and their mitigation strategies
Published 2018“…This dissertation shown six causes of reworks and five mitigation techniques to reduce the reworks. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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Causes of Delay in Construction Projects in Oil and Gas Construction Industry
Published 2017“…Dispute management processes appeared to be another major cause of delay. Lastly, it was established that there were no active formal means of delay analysis. …”
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Brucellar cervical epidural abscess - A rare cause of neck pain
Published 2021“…<p dir="ltr">Brucellosis, is a zoonosis infection with a planetary distribution, caused by facultative intracellular bacteria of the genus Brucella, thus has a variable clinical presentation. …”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
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Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burd...
Published 2021“…Optimal child survival metrics were developed by age, sex, and cause of death across all GBD location-years. The first metric is a global optimum and is based on the lowest observed mortality, and the second is a survival potential frontier that is based on stochastic frontier analysis of observed mortality and Healthcare Access and Quality Index.…”
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Causes of Undergraduate Students’ Underachievement in a Gulf Cooperation Council Country (GCC) University
Published 2022“…As part of the Intrusive Intervention Program, students were required to complete an Academic Success Plan that delineated academic, personal, social, career, and other academic underachievement reasons. Based on 5,040 students’ responses that indicated their academic underachievement causes, findings reported that students perceived academic factors as the most recurrent reason for academic underachievement. …”
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Investigating the Quality Combined Effect of Root Cause Analysis (RCA) in Quality Management in Manufacturing Firms
Published 2024“…This research delves into the application of Total Quality Management (TQM) and Six Sigma DMAIC methodologies to optimise the manufacturing process of LED High Bay lights within a Golf Country-based factory. The study aimed to identify and address the root causes of product defects, primarily focusing on electrical surge protection issues. …”
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
Published 2006Get full text
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Novel Synonymous Variant in<i> IL7R</i> Causes Preferential Expression of the Soluble Isoform
Published 2024“…This case demonstrates the value of reanalyzing genetic data based on the clinical phenotype and highlights the significance of functional studies in determining the pathogenicity of genetic variants.…”
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
Published 2025“…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…”
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Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through...
Published 2021“…Results The method of measuring reflectivity is good to excellent reliability for all regions of interest except the fourth. The mean reflectivity of the choriocapillaris and Sattler’s layer in amblyopic eyes were significantly lower than in healthy eyes (p = 0.003 and p = 0.008 respectively). …”
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A GHRHR founder mutation causes isolated growth hormone deficiency type IV in a consanguineous Pakistani family
Published 2023“…<h3>Background</h3><p dir="ltr">Isolated growth hormone deficiency (IGHD) is caused by a severe shortage or absence of growth hormone (GH), which results in aberrant growth and development. …”
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Invasive Milk Thistle (Silybum marianum (L.) Gaertn.) Causes Habitat Homogenization and Affects the Spatial Distribution of Vegetation in the Semi-Arid Regions of Northern Pakistan
Published 2022“…The community composition significantly changes with changes in invasion intensity. …”
