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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…To assess the effect of kefir on cancer metastasis, wound‑healing and time‑lapse movies, in addition to collagen‑based invasion assay, were used. The results show that cell‑free fractions of kefir exhibit an anti‑proliferative effect on Caco‑2 and HT‑29 cells. …”
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Scaffold‑based 3D cell culture models in cancer research
Published 2024“…Three-dimensional (3D) cell cultures have emerged as valuable tools in cancer research, offering significant advantages over traditional two-dimensional (2D) cell culture systems. …”
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Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…Furthermore, treatment of MDA-MB-231 cells with either fraction significantly reduced the level of phosphorylated Erk but did not show any effect on phosphorylated Akt. …”
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Asynchronous MMC based parallel SA schemes for multiobjective standard cell placement
Published 2006“…Lee (1996) and applied to standard-cell placement as presented in J. Chandy et al. (1997), The schemes are applied to solve the multi-objective standard cell placement problem using an inexpensive cluster-of-workstations environment. …”
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Board changes and CEO turnover
Published 2014“…For firms that decrease independence, the CEO turnover performance sensitivity significantly decreases following SOX. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…<p dir="ltr">NanoLuc (NLuc) <u>luciferase</u> has found extensive application in designing a range of <u>biologica</u><u>l</u><u> assays,</u> including <u>gene expression analysis</u>, protein-protein interaction, and protein conformational changes due to its enhanced brightness and small size. …”
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Single-cell protein production from purple non-sulphur bacteria-based wastewater treatment
Published 2022“…<p>Large-scale production of single-cell protein (SCP) has the potential not only to solve some of the food insecurity and water scarcity crises that plague a significant portion of our world today but also holds the promise to reduce the cost associated with the treatment of industrial and agricultural wastewater. …”
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Novel Whole-Cell Inactivated Neisseria Gonorrhoeae Microparticles as Vaccine Formulation in Microneedle-Based Transdermal Immunization
Published 2018“…Here we report that whole-cell-based gonococcal microparticle vaccine loaded in dissolvable microneedles for transdermal administration induced significant increase in antigen-specific IgG antibody titers and antigen-specific CD4 and CD8 T lymphocytes in mice compared to gonococcal antigens in solution or empty microneedles. …”
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Targeting solid tumor cells with novel photosensitive ruthenium-based metal-organic compounds. (c2016)
Published 2016“…This study aims to find the most efficient Ru-based compounds on a set of 6 cell lines from different solid tumors. …”
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Performance Optimization in Lead-Free Perovskite Solar Cell: A Comparative Approach
Published 2025“…<p dir="ltr">Perovskite solar cells (PSCs) technology posses potential among numerous solar cells due to their promising sustainable energy solutions. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Global gene expression profiling of LY411575-treated cells revealed changes in multiple signaling pathways, including focal adhesion, insulin, TGFβ, IL6, and Notch signaling, and decreased the expression of genes associated with functional categories of tissue development. …”
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Vocal Changes in Patients With Polycystic Ovary Syndrome
Published 2011“…There was no statistically significant difference in the acoustic parameters except for an increase in the relative average perturbation (P value = 0.035) and a decrease in maximum phonation time (P value = 0.001) in patients with PCOS. …”
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Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015)
Published 2016“…Of the four free ligands tested (L-I, L-II, L-III and L-IV corresponding to Ru-I, Ru-II, Ru-III and Ru-IV, respectively), significant cytotoxic activity was detected in eight out of nine cell lines, only with L-I and L-II, (IC50 values in the low μM range for L-I and reaching the nM range for L-II). …”
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Prostate-based biofluids for the detection of prostate cancer: A comparative study of the diagnostic performance of cell-sourced RNA biomarkers
Published 2016“…Conclusion PEUW contains prostatic material, but has limited diagnostic accuracy when considering cell-derived DNA analysis. PCA3-based markers in ejaculate are comparable to serum PSA and digital rectal examination–urine markers.…”
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Safety and efficacy of chimeric antigen receptor T-cell therapy for acute myeloid leukemia: A subgroup based meta-analysis
Published 2024“…</p><p><br></p><h3>Results</h3><p dir="ltr">Our search yielded studies encompassing 57 AML patients treated with CAR T-cell therapy. The meta-analysis revealed a 48% incidence of complete remission with CAR T-cell therapy, varying significantly across subgroups based on study design, location, prior transplantation, conditioning regimen, and CAR T-cell source. …”
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Essays on the effect of excess compensation and governance changes on firm value
Published 2012“…This dissertation consists of three essays on the effect of excess compensation and corporate governance changes on the firm’s performance. The first paper utilizes a cost minimization stochastic frontier approach to investigate the efficiency of director total compensation. …”
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Energy-Efficient Cell Association and Load Balancing for Low Battery Users in Heterogeneous Cellular Networks
Published 2025“…The proposed battery based cell association models perform well in favor of LBUs and clearly show the significance of the proposed approach.…”