A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”

Decreased Analgesic Requirements in Super Morbidly Versus Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy by Hamed Elgendy (14148846)

Both decreasing interstructural space size and increasing total cover increase shrimp abundance on artificial structures deployed in a UAE seagrass bed by Bartholomew, Aaron

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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

“…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…”

L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression by Rached, Johnny

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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”

The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... by Wesal Habbab (17346961)

“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Vijay Ganji (8710491)

Identifying and Assessing the Significance of Digital Twin Enablers in the Construction Industry by Isbaih, Sara Samir

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Addition of sphingosine-1-phosphate to human oocyte culture medium decreases embryo fragmentation by Zreik, Tony

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Editorial: At the Crossroads: Lessons and Challenges in Computational Social Science by Javier Borge-Holthoefer (211484)

“…At the turn of the century, however, it was clear that huge challenges—and new opportunities— lied ahead: the digital communication technologies, and their associated data deluge, began to nurture those models with empirical significance. …”

QFD-based optimization model for mitigating sustainable supply chain management adoption challenges for Bangladeshi RMG industries by Md Al Amin (17808299)

“…The implications extend beyond the RMG sector, offering a replicable model for other industries and regions facing similar sustainability challenges.…”

Implementing a collaborative care model for child and adolescent mental health in Qatar: Addressing workforce and access challenges by Mohamed Adil Shah Khoodoruth (14589828)

“…This commentary explores the model’s feasibility, addressing challenges like workforce shortages and psychotropic prescribing processes. …”

Survey of Multimodal Federated Learning: Exploring Data Integration, Challenges, and Future Directions by Mumin Adam (22466626)

“…Traditional machine learning (ML) models rely on centralized architectures, which, while powerful, often present significant privacy risks due to the centralization of sensitive data. …”

Diabetic Foot Ulcer Detection: Combining Deep Learning Models for Improved Localization by Rusab Sarmun (17632269)

Applications of bioconvection for tiny particles due to two concentric cylinders when role of Lorentz force is significant by Lei Zhang (38117)

Impact of AI and Dynamic Ensemble Techniques in Enhancing Healthcare Services: Opportunities and Ethical Challenges by Haseeb Javed (18576340)

“…Dynamic ensemble techniques, which leverage multiple predictive models to improve outcome accuracy, offer significant promise in addressing the complexities of patient data and disease manifestations. …”

Investigations on Entrepreneurship Needs, Challenges, and Models for Countries in Transition to Sustainable Development from Resource-Based Economy—Qatar as a Case by Mohammad I. Al-Housani (19170967)

Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment by Amal Sabouni (17046236)

“…In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …”

Deep random vector functional link transformer network with multiple output layers for significant wave height forecasting by Aryan Bhambu (18767731)

“…<p>Accurate control of wave energy devices relies heavily on precise forecasts of wave heights, yet the dynamic and fluctuating nature of historical wave data presents significant challenges to achieving this precision. …”