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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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Pharmacist Role in Hypertension Management in the Community Setting: Questionnaire Development, Validation, and Application
Published 2023“…Pharmacists can play a substantial role in decreasing the burden of the disease.</p><h3>Purpose</h3><p dir="ltr">The primary aim of this study was to develop and validate a scale assessing the pharmacist role in hypertension management in the community pharmacy setting. …”
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Thermal challenges in lithium-ion battery technology: Investigating performance and thermal stability
Published 2025“…Results show a significant reduction in discharge capacity, decreasing from 38.12 mAh in the first cycle to 24.36 mAh after 350 cycles at 55 °C, corresponding to a 36.1 % capacity loss. …”
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Role of family in supporting children with mental disorders in Qatar
Published 2023“…Age has no statistically significant effect on the role of family members in supporting people with mental disorders.…”
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Addressing Challenges of Distance Learning in the Pandemic with Edge Intelligence Enabled Multicast and Caching Solution
Published 2022“…We debate the role of Edge Intelligence (EI) for enabling multicast and edge caching for distance learning to complement the performance of the proposed VNF architecture. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 Cases
Published 2024“…Liver enzyme and bilirubin levels were significantly higher in the advanced types. Preoperative diagnosis was achieved in 70% of patients, with MRCP and ERCP being the most effective diagnostic tools. …”
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PGAP3 Associated with Hyperphosphatasia with Mental Retardation Plays a Novel Role in Brain Morphogenesis and Neuronal Wiring at Early Development
Published 2020“…Here, we report a novel homozygous nonsense mutation in PGAP3 (c.265C>T-p.Gln89*), in a 3-year-old boy with unique novel clinical features. These include decreased intrauterine fetal movements, dysgenesis of the corpus callosum, olfactory bulb agenesis, dysmorphic features, cleft palate, left ear constriction, global developmental delay, and hypotonia. …”
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Exploring the Role of Perceived Organizational Injustice and Organizational Identification in the Impact of Discretionary HR Practices on Counterproductive Behaviors: Evidence from...
Published 2025“…It investigates how customized, flexible HR practices are resource-enhancing tools that decrease workplace deviant behaviors. The study uses survey responses from 214 Lebanese employees working in different sectors to fill a significant knowledge gap in HR studies, primarily focusing on Western business settings. …”
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masterThesis -
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Teachers’ Job Satisfaction in Instructional Delivery Modalities, and the Role of School Leaders: a Study among Selected Private Schools in Abu Dhabi.
Published 2022“…The second purpose of the study is to navigate the role of school leadership to help teachers cope with these models and find out the best ways they can increase their level of satisfaction. …”
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Deciphering the In vitro Role of microRNAs miR-21-3p and miR-222-5p In the Regulation of Clostridioides difficile Flagellin-Induced Inflammation
Published 2024“…Functional assays revealed that miR-222-5p overexpression led to a significant increased expression of key pro-inflammatory cytokines, including IL-8 and TNF-α, while knockdown of these miRNAs resulted in their decreased expression. …”
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Investigating the Role of Acetyl-CoA Synthetase Short Chain Family Member 2 (ACSS2) in Inflammatory Bowel Disease: Expression in Clinical Samples and Insights from In Vitro Models
Published 2025“…Acetyl-CoA Synthetase Short Chain Family Member 2 (ACSS2), an enzyme converting acetate to acetyl-CoA, is known to regulate gene transcription and cellular processes through its nuclear localization under metabolic stress. However, its role in IBD remains unclear. In this study, immunohistochemistry of colon samples from UC patients revealed significantly elevated expression and nuclear localization of ACSS2 in inflamed tissues compared to non-inflamed regions, suggesting its involvement in IBD pathogenesis. …”
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