Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways by Hadeel, Kheraldine

“…HER2-positive breast cancer is one of its most challenging subtypes, forming around 15–25% of the total cases. …”
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Neratinib and metformin: A novel therapeutic approach against HER2-Positive Breast Cancer by Kheraldine, Hadeel

“…BackgroundHER2-positive breast cancer (BC) is highly aggressive with a poor prognosis. …”
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HER2-positive apocrine carcinoma of the breast: a population-based analysis of treatment and outcome by Faruk Skenderi (6616190)

“…HER2+/APO tumors tend to have a less aggressive phenotype and a more favorable outcome despite a markedly lower ER/PR positivity.</p><h2>Other Information</h2> <p> Published in: Breast Cancer Research and Treatment<br> License: <a href="https://creativecommons.org/licenses/by/4.0" target="_blank">https://creativecommons.org/licenses/by/4.0</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1007/s10549-022-06578-4" target="_blank">http://dx.doi.org/10.1007/s10549-022-06578-4</a></p>…”

Ratio between positive lymph nodes and total excised axillary lymph nodes as an independent prognostic factor for overall survival in patients with nonmetastatic lymph node-positiv... by Dimassi, Hani

“…The status of the axillary lymph nodes in nonmetastatic lymph node-positive breast cancer (BC) patients remains the single most important determinant of overall survival (OS). …”
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Gene Expression and miRNAs Profiling: Function and Regulation in Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Breast Cancer by Rasha M. Sareyeldin (18131371)

“…Despite the anti-HER2 and cytotoxic chemotherapy, HER2 subtype is an aggressive disease with significant mortality. Recent advances in molecular biology techniques, including gene expression profiling, proteomics, and microRNA analysis, have been extensively used to explore the underlying mechanisms behind human breast carcinogenesis and metastasis including HER2-positive breast cancer, paving the way for developing new targeted therapies. …”

Targeting HER2-positive breast cancer cells by a combination of dasatinib and BMS-202: Insight into the molecular pathways by Hadeel Kheraldine (14231609)

“…</p><h3>Conclusion</h3><p dir="ltr">Our findings implicate that a combination of DA and BMS-202 could have a significant impact on the management of HER2-positive breast cancer.…”

Substantial cell apoptosis provoked by naked PAMAM dendrimers in HER2-positive human breast cancer via JNK and ERK1/ERK2 signalling pathways by Hadeel Kheraldine (14231609)

“…<p>HER2-positive breast cancer is one of its most challenging subtypes, forming around 15–25% of the total cases. …”

Board changes and CEO turnover by Dah, Mustafa A.

“…For firms that decrease independence, the CEO turnover performance sensitivity significantly decreases following SOX. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…<p dir="ltr">NanoLuc (NLuc) <u>luciferase</u> has found extensive application in designing a range of <u>biologica</u><u>l</u><u> assays,</u> including <u>gene expression analysis</u>, protein-protein interaction, and protein conformational changes due to its enhanced brightness and small size. …”

Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Global gene expression profiling of LY411575-treated cells revealed changes in multiple signaling pathways, including focal adhesion, insulin, TGFβ, IL6, and Notch signaling, and decreased the expression of genes associated with functional categories of tissue development. …”

Vocal Changes in Patients With Polycystic Ovary Syndrome by Hannoun, Antoine

“…There was no statistically significant difference in the acoustic parameters except for an increase in the relative average perturbation (P value = 0.035) and a decrease in maximum phonation time (P value = 0.001) in patients with PCOS. …”
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Breast cancer screening in Lebanon: Understanding knowledge, attitudes and barriers by Elias-Rizk, Tamina

“…Background Breast cancer (BC) has been increasing in both prevalence and incidence in Lebanon. …”
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Evaluation of Estrone Liposomes using Microfluidics for Breast Cancer Therapy by Al Bostami, Rouba D.

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Discrimination of breast cancer from benign tumours using Raman spectroscopy by Fiona M. Lyng (2189614)

“…Breast cancer is diagnosed by histopathological examination of breast biopsy material but this is subjective and relies on morphological changes in the tissue. …”

Ultrasound triggered release of Trastuzumab-conjugated immunoliposomes targeting breast cancer by Ahmed, Amal Elsadig Elamir

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Correction: Discrimination of breast cancer from benign tumours using Raman spectroscopy by Fiona M. Lyng (2189614)

“…<p dir="ltr">Correction to: Discrimination of breast cancer from benign tumours using Raman spectroscopy. …”

Essays on the effect of excess compensation and governance changes on firm value by Dah, Mustafa A.

“…This dissertation consists of three essays on the effect of excess compensation and corporate governance changes on the firm’s performance. The first paper utilizes a cost minimization stochastic frontier approach to investigate the efficiency of director total compensation. …”
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Diagnostic test accuracy of AI-assisted mammography for breast imaging: a narrative review by Daksh Dave (17949239)

“…The motivation for this research lies in addressing the need for enhanced diagnostic tools in breast cancer screening, where early detection can significantly impact patient outcomes. …”

Rhus coriaria L. (Sumac) Demonstrates Oncostatic Activity in the Therapeutic and Preventive Model of Breast Carcinoma by Peter Kubatka (11008854)

“…Finally, only in lower sumac dose, significant decreases in methylation status of three out of five gene promoters–ATM, PTEN, and TIMP3 (PITX2 and RASSF1 promoters were not changed). …”

Metabolomics of Dynamic Changes in Insulin Resistance Before and After Exercise in PCOS by Anna Halama (545988)

“…While compering within the groups, no significant changes in the amino acid levels before and after exercise were observed. …”