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Significance of Avicennia Marina in the Arabian Gulf Environment: A Review
Published 2025“…However, in the past two decades Gulf mangroves have been facing significant threats, including extensive coastal development, shoreline modification by establishing marinas and ports, and climate change-associated impacts such as sea-level rise and altered precipitation patterns, which pose significant risks to this fragile ecosystem. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
Published 2025“…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”
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Attitudes towards climate change and energy sources in oil exporters
Published 2021“…Switching to energy mixes that use more non-fossil fuels is critical to reduce greenhouse gas emissions to tackle climate change. Climate change poses a major challenge to oil exporting Gulf countries, like the rest of the world, but research on human views on energy and climate change is limited. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Plasma and urine metabolomic analyses in aortic valve stenosis reveal shared and biofluid-specific changes in metabolite levels
Published 2020“…Following metabolite assignment, we observed significant changes in the concentration of known metabolites in urine (n = 14) and plasma (n = 15) that distinguish the metabolomic profiles of AVS patients from healthy controls. …”
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Implementing and leading technology-driven pedagogical change: A Study among Teachers from Selected Schools in Abu Dhabi
Published 2025“…Findings reveal that visionary leadership, strategic planning and collaborative professional development are critical for successful technology integration, while resistance to change and resource limitations pose significant challenges. …”
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Impacts of climate change on the global spread and habitat suitability of <i>Coxiella burnetii</i>: Future projections and public health implications
Published 2025“…<h3>Introduction</h3><p dir="ltr"><i><u>Coxiella burnetii</u></i><i><u>,</u></i> an intracellular zoonotic bacterium, affectsing various livestock and <u>wildlife</u> species and poses significant risks to human health. This study aims to assess how <u>climate change</u> could impact the global distribution and habitat suitability of <i>Coxiella burnetii</i>, the pathogen responsible for <u>Q fever</u>. …”
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Unveiling the Nexus Between Land Use, Land Surface Temperature, and Carbon Footprint: A Multi-Scale Analysis of Building Energy Consumption in Arid Urban Areas
Published 2024“…<p dir="ltr">Urbanization and land use changes, especially in arid environments, significantly impact local climate and energy demand. …”
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Hydrogen energy systems: Technologies, trends, and future prospects
Published 2024“…Additionally, <u>hydrogen storage</u> poses its own challenges, requiring conditions of up to 700 bar or temperatures below −253 °C. …”
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Editorial: Special Issue - Economics in Digital Construction
Published 2024“…Consequently, there is a need signaled for structural reforms in the latter, to improve the rate of integration of digitalisation in the construction sector (Kapogiannis, et al., 2023). Climate change is also a factor that now poses challenges for the construction sector, with digitalisation a key element able to address these challenges.…”
