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Photoactivatable RuII Complex Bearing 2,9‐Diphenyl‐1,10‐phenanthroline: Unusual Photochemistry and Significant Potency on Cisplatin‐Resistant Cell Lines
Published 2018“…Complex 1 demonstrated only marginal activity in the dark; its cytotoxicity increased significantly upon photoactivation with a high phototoxicity index (PI = [IC50 dark]/[IC50 light]) ranging from 39.2‐fold in A549 to over 100‐fold in MDA‐MB‐231. …”
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Challenges and practices identification in complex outsourcing relationships: A systematic literature review
Published 2022“…<p dir="ltr">Complex IT outsourcing relationships aptitude several benefits such as increased cost likelihood and lowered costs, higher scalability and flexibility upon demand. …”
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The Role of Project Management Soft Skills in Increasing Project Success
Published 2017“…As the world economy shifts towards an increasingly globalised market, the degree of competition becomes a more significant challenge which organisations face. …”
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Structural interactions of complex proteins with trehalose: mechanisms for improving the multilevel structure and functional properties of lentil-quinoa protein complexes
Published 2024“…The water solubility and digestibility of the latter conjugate-derived lentil and quinoa complex increased from 75.1 to 80% and 75 to 80.3%, respectively. …”
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Board changes and CEO turnover
Published 2014“…For firms that decrease independence, the CEO turnover performance sensitivity significantly decreases following SOX. …”
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Habitat Complexity Influences the Microhabitat Choices of Desert Beetles
Published 2011“…The median number of large beetles was significantly higher in medium-complexity artificial treatments compared with both low- and high-complexity treatments. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…<p dir="ltr">NanoLuc (NLuc) <u>luciferase</u> has found extensive application in designing a range of <u>biologica</u><u>l</u><u> assays,</u> including <u>gene expression analysis</u>, protein-protein interaction, and protein conformational changes due to its enhanced brightness and small size. …”
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Molecular forces driving protein complexation of lentil and whey proteins: Structure-function relationships of trehalose-conjugated protein complexes on protein digestibility and s...
Published 2024“…The amide group I, conformation protein, and tertiary structure of the trehalose-conjugated lentil-whey protein complexes (T-LWPs) showed significant changes (P < 0.05). …”
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Increased Levels of Circulating and Tumor-Infiltrating Granulocytic Myeloid Cells in Colorectal Cancer Patients
Published 2016“…Flow cytometric analysis was performed to examine the expression of different myeloid markers in fresh peripheral blood samples from CRC patients and HDs, and tissue-infiltrating immune cells from CRC patients. We found significantly higher levels of cells expressing myeloid markers and lacking the expression of major histocompatibility complex class II molecule HLA-DR in blood and tumor of CRC patients. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Global gene expression profiling of LY411575-treated cells revealed changes in multiple signaling pathways, including focal adhesion, insulin, TGFβ, IL6, and Notch signaling, and decreased the expression of genes associated with functional categories of tissue development. …”
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Vocal Changes in Patients With Polycystic Ovary Syndrome
Published 2011“…There was no statistically significant difference in the acoustic parameters except for an increase in the relative average perturbation (P value = 0.035) and a decrease in maximum phonation time (P value = 0.001) in patients with PCOS. …”
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Implications of the medication regimen complexity index score on hospital readmissions in elderly patients with heart failure: a retrospective cohort study
Published 2023“…Therefore, it can be concluded that the medication regimen complexity index does not appear to be a significant predictor of hospital readmission or mortality in this population.…”
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Essays on the effect of excess compensation and governance changes on firm value
Published 2012“…This dissertation consists of three essays on the effect of excess compensation and corporate governance changes on the firm’s performance. The first paper utilizes a cost minimization stochastic frontier approach to investigate the efficiency of director total compensation. …”
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Effects of habitat complexity on the abundance, species richness and size of darkling beetles (Tenebrionidae) in artificial vegetation
Published 2016“…We deployed artificial vegetation with 4 different interstructural space widths (complexities): 6, 10, 14 and 27 mm. At the high levels of habitat complexity used in this study, the main effect of increasing complexity was excluding beetles from higher complexity treatments, particularly larger beetle species. …”
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Phenotypic and Genotypic Characterization of Candida parapsilosis complex isolates from a Lebanese Hospital
Published 2023“…Our results showed that resistant isolates had no increased ergosterol content, or chitin deposition, no significant difference in virulence, but exhibited an increase in biofilm content compared with sensitive isolates. …”
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Metabolomics of Dynamic Changes in Insulin Resistance Before and After Exercise in PCOS
Published 2019“…While compering within the groups, no significant changes in the amino acid levels before and after exercise were observed. …”
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Enhanced cellular uptake and photochemotherapeutic potential of a lipophilic strained Ru(II) polypyridyl complex
Published 2019“…Cellular uptake of complex 1 and the free BC ligand were found to be significantly facilitated as evidenced by 400–600 fold increase in concentration of the compounds inside the cells relative to the extracellular culture medium. …”
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