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Detection of statistically significant network changes in complex biological networks
Published 2017“…It can happen that due to gene mutations, as for example when cancer progresses, the gene expression network undergoes some amount of localized re-wiring. …”
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Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery
Published 2019“…Normalization of fasting glucose and HbA1c following bariatric surgery (short-term diabetes remission) was defined as withdrawal of anti-diabetic medication and fasting glucose < 100 mg/dL (5.6 mmol/L) or HbA1c < 6.0%. MicroRNA expression was determined by quantitative polymerase chain reaction and tested for significant changes after surgery.…”
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The Use of the Gene Expression Omnibus (GEO) Database to Study Gene Expression and Methylation Patterns in Cases of Preterm Birth and Associated Diseases
Published 2023“…</p> <h3>Results</h3> <p>Of the 8 datasets, 3 displayed significant changes in expression patterns after application of the filtering criteria. …”
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Expression of microRNA in follicular fluid in women with and without PCOS
Published 2019“…<p>Several studies have shown the expression of small non-coding microRNA (miRNA) changes in PCOS and their expression in follicular fluid has been described, though the number of studies remains small. …”
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Analysis of facial emotion expression in eating occasions using deep learning
Published 2023“…The emotion felt while eating has a significant impact on our lives and affects different health conditions such as obesity. …”
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Gene expression data analysis identifies multiple deregulated pathways in patients with asthma
Published 2018“…The data highlight the multifactorial nature of asthma, but revealed no significant overlap with the gene expression profiles from different datasets interrogated in current studies. …”
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Differentially expressed miRNA profiles of serum derived extracellular vesicles from patients with acute ischemic stroke
Published 2024“…An enrichment analysis was conducted to delineate the networks and biological pathways implicated by differentially expressed microRNAs. ResultsFive miRNAs were differentially expressed between stroke (AIS) versus control (HC). hsa-let-7b-5p, hsa-miR-16-5p, and hsa-miR-320c were upregulated, whereas hsa-miR-548a-3p and hsa-miR-6808-3p, with no previously reported changes in stroke were downregulated. …”
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Differentially expressed miRNA profiles of serum derived extracellular vesicles from patients with acute ischemic stroke
Published 2024“…An enrichment analysis was conducted to delineate the networks and biological pathways implicated by differentially expressed microRNAs. </p><h3>Results</h3><p dir="ltr">Five miRNAs were differentially expressed between stroke (AIS) versus control (HC). hsa-let-7b-5p, hsa-miR-16-5p, and hsa-miR-320c were upregulated, whereas hsa-miR-548a-3p and hsa-miR-6808-3p, with no previously reported changes in stroke were downregulated. …”
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Using Artificial Intelligence to Understand What Causes Sentiment Changes on Social Media
Published 2021“…Sentiment Analysis tools allow decision-makers to monitor changes of opinions on social media towards entities, events, products, solutions, and services. …”
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Morphological changes in amblyopic eyes in choriocapillaris and Sattler’s layer in comparison to healthy eyes, and in retinal nerve fiber layer in comparison to fellow eyes through...
Published 2021“…Results The method of measuring reflectivity is good to excellent reliability for all regions of interest except the fourth. The mean reflectivity of the choriocapillaris and Sattler’s layer in amblyopic eyes were significantly lower than in healthy eyes (p = 0.003 and p = 0.008 respectively). …”
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Genome-wide differential expression profiling of long non-coding RNAs in FOXA2 knockout iPSC-derived pancreatic cells
Published 2023“…Furthermore, we constructed co-expression networks linking significantly downregulated lncRNAs with differentially expressed pancreatic mRNAs.…”
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Treatment with decitabine induces the expression of stemness markers, PD-L1 and NY-ESO-1 in colorectal cancer: potential for combined chemoimmunotherapy
Published 2023“…Of these, a chemotherapeutic demethylating agent, Decitabine (DAC), has been reported to induce a dual effect on both DNA demethylation and histone changes leading to an increased expression of target biomarkers, thus making it an attractive anti-tumorigenic drug.…”
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iPSC-Derived Pancreatic Progenitors Lacking FOXA2 Reveal Alterations in miRNA Expression Targeting Key Pancreatic Genes
Published 2023“…Gene ontology (GO) and KEGG pathways analyses were performed on the differentially expressed genes (DEGs). For differentially expressed miRNAs, a fold-change of >2 with a P-value <0.05 was used as a cutoff to determine the differentially expressed miRNAs in FOXA2–/–hiPSCs versus WT-hiPSCs. …”
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Genome-wide differential expression profiling of long non-coding RNAs (lncRNAs) in pancreatic cells derived from FOXA2-/- iPSCs
Published 2023“…However, whether these changes are associated with alterations in the expression profile of the long non-coding RNAs (lncRNAs) remains unclear.…”
