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Detection of statistically significant network changes in complex biological networks
Published 2017“…It can happen that due to gene mutations, as for example when cancer progresses, the gene expression network undergoes some amount of localized re-wiring. …”
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Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery
Published 2019“…Normalization of fasting glucose and HbA1c following bariatric surgery (short-term diabetes remission) was defined as withdrawal of anti-diabetic medication and fasting glucose < 100 mg/dL (5.6 mmol/L) or HbA1c < 6.0%. MicroRNA expression was determined by quantitative polymerase chain reaction and tested for significant changes after surgery.…”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Global gene expression profiling of LY411575-treated cells revealed changes in multiple signaling pathways, including focal adhesion, insulin, TGFβ, IL6, and Notch signaling, and decreased the expression of genes associated with functional categories of tissue development. …”
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The Use of the Gene Expression Omnibus (GEO) Database to Study Gene Expression and Methylation Patterns in Cases of Preterm Birth and Associated Diseases
Published 2023“…</p> <h3>Results</h3> <p>Of the 8 datasets, 3 displayed significant changes in expression patterns after application of the filtering criteria. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…<p dir="ltr">NanoLuc (NLuc) <u>luciferase</u> has found extensive application in designing a range of <u>biologica</u><u>l</u><u> assays,</u> including <u>gene expression analysis</u>, protein-protein interaction, and protein conformational changes due to its enhanced brightness and small size. …”
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Expression of microRNA in follicular fluid in women with and without PCOS
Published 2019“…<p>Several studies have shown the expression of small non-coding microRNA (miRNA) changes in PCOS and their expression in follicular fluid has been described, though the number of studies remains small. …”
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Analysis of facial emotion expression in eating occasions using deep learning
Published 2023“…The emotion felt while eating has a significant impact on our lives and affects different health conditions such as obesity. …”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
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Gene expression data analysis identifies multiple deregulated pathways in patients with asthma
Published 2018“…The data highlight the multifactorial nature of asthma, but revealed no significant overlap with the gene expression profiles from different datasets interrogated in current studies. …”
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
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Differentially expressed miRNA profiles of serum derived extracellular vesicles from patients with acute ischemic stroke
Published 2024“…An enrichment analysis was conducted to delineate the networks and biological pathways implicated by differentially expressed microRNAs. ResultsFive miRNAs were differentially expressed between stroke (AIS) versus control (HC). hsa-let-7b-5p, hsa-miR-16-5p, and hsa-miR-320c were upregulated, whereas hsa-miR-548a-3p and hsa-miR-6808-3p, with no previously reported changes in stroke were downregulated. …”
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Differentially expressed miRNA profiles of serum derived extracellular vesicles from patients with acute ischemic stroke
Published 2024“…An enrichment analysis was conducted to delineate the networks and biological pathways implicated by differentially expressed microRNAs. </p><h3>Results</h3><p dir="ltr">Five miRNAs were differentially expressed between stroke (AIS) versus control (HC). hsa-let-7b-5p, hsa-miR-16-5p, and hsa-miR-320c were upregulated, whereas hsa-miR-548a-3p and hsa-miR-6808-3p, with no previously reported changes in stroke were downregulated. …”
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Using Artificial Intelligence to Understand What Causes Sentiment Changes on Social Media
Published 2021“…Sentiment Analysis tools allow decision-makers to monitor changes of opinions on social media towards entities, events, products, solutions, and services. …”
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