A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”

Decreased Analgesic Requirements in Super Morbidly Versus Morbidly Obese Patients Undergoing Laparoscopic Sleeve Gastrectomy by Hamed Elgendy (14148846)

Both decreasing interstructural space size and increasing total cover increase shrimp abundance on artificial structures deployed in a UAE seagrass bed by Bartholomew, Aaron

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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

“…</p><p dir="ltr">Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex: Frontiers in Molecular Biosciences: <a href="https://dx.doi.org/10.3389/fmolb.2022.1018464" rel="noreferrer" target="_blank">https://dx.doi.org/10.3389/fmolb.2022.1018464</a>, published online 19 October 2022.…”

L1-CAM knock-down radiosensitizes neuroblastoma IMR-32 cells by simultaneously decreasing MycN, but increasing PTEN protein expression by Rached, Johnny

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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”

The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... by Wesal Habbab (17346961)

“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”

Serum Vitamin D Concentration ≥75 nmol/L Is Related to Decreased Cardiometabolic and Inflammatory Biomarkers, Metabolic Syndrome, and Diabetes; and Increased Cardiorespiratory Fitn... by Vijay Ganji (8710491)

Arnold-Chiari malformation and significant lumbar disc prolapse in pregnancy: A case report and literature review by Albert Adu Opoku (17280640)

Effect of clinical hyperthyroidism and hypothyroidism on patent diabetes. 59 cases by Hirbli, K.

“…A higher proportion of vitiligo was also noted: 14% in the total patient population reported, and 18% in insulin-treated patients.…”
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Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 Cases by Yousef Yahia (19756989)

“…<h3>Background</h3><p dir="ltr">Mirizzi Syndrome (MS) is a rare complication of gallstone disease that poses diagnostic and management challenges.…”

Three cases of chronic photodermatitis successfully treated with upadacitinib by Hissa Al-Marri (22827287)

“…Here, we report three cases of chronic photodermatitis treated with upadacitinib, a selective Janus kinase 1 inhibitor, as monotherapy, which resulted in fast, significant and sustainable improvement of signs and symptoms, with a favourable safety and tolerability profile.…”

Addition of sphingosine-1-phosphate to human oocyte culture medium decreases embryo fragmentation by Zreik, Tony

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Smoking-related complications among COVID-19 cases: a population-based survey in Qatar by Nada Adli (15898914)

“…Conclusion: Even with limited statistical significance between smoking history and COVID-19 disease severity and outcome, clinical risk differences were observed among smokers. …”

Clinical characteristics and outcomes of patients with TSH-secreting pituitary adenoma and Graves’ disease - a case report and systematic review by Adeel Ahmad Khan (14152953)

The case for disaster medicine training by Nature Research (16552612)

Applications of bioconvection for tiny particles due to two concentric cylinders when role of Lorentz force is significant by Lei Zhang (38117)

Abdominal cocoon syndrome: a case report by Fazeela Bibi (22916561)

“…The diagnosis was confirmed intraoperatively, and management involved membrane excision, adhesiolysis, and a simple appendectomy for a secondarily involved appendix. This case is clinically significant for demonstrating tailored intraoperative decision-making; the appendicular involvement was correctly identified as a secondary consequence of the cocoon’s chronic inflammation, thus avoiding an unnecessary hemicolectomy. …”

Immune thrombocytopenia associated with tuberculosis – A case report by Adeel Ahmad Khan (14152953)

Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment by Amal Sabouni (17046236)

“…In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …”