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Effect of clinical hyperthyroidism and hypothyroidism on patent diabetes. 59 cases
Published 1983“…A higher proportion of vitiligo was also noted: 14% in the total patient population reported, and 18% in insulin-treated patients.…”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Mirizzi Syndrome: Mastering the Challenge, Characterization and Management Outcomes in a Retrospective Study of 60 Cases
Published 2024“…<h3>Background</h3><p dir="ltr">Mirizzi Syndrome (MS) is a rare complication of gallstone disease that poses diagnostic and management challenges.…”
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Three cases of chronic photodermatitis successfully treated with upadacitinib
Published 2025“…Here, we report three cases of chronic photodermatitis treated with upadacitinib, a selective Janus kinase 1 inhibitor, as monotherapy, which resulted in fast, significant and sustainable improvement of signs and symptoms, with a favourable safety and tolerability profile.…”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Smoking-related complications among COVID-19 cases: a population-based survey in Qatar
Published 2023“…Conclusion: Even with limited statistical significance between smoking history and COVID-19 disease severity and outcome, clinical risk differences were observed among smokers. …”
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Abdominal cocoon syndrome: a case report
Published 2025“…The diagnosis was confirmed intraoperatively, and management involved membrane excision, adhesiolysis, and a simple appendectomy for a secondarily involved appendix. This case is clinically significant for demonstrating tailored intraoperative decision-making; the appendicular involvement was correctly identified as a secondary consequence of the cocoon’s chronic inflammation, thus avoiding an unnecessary hemicolectomy. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …”
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Brucellosis in older person: a case report from Qatar
Published 2022“…Human brucellosis is quite uncommon in Elderly in Qatar.</p><h3>Case report</h3><p dir="ltr">This report describes a case of Brucellosis in acute geriatric unit under Rumailah Hospital in Qatar. …”
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Association of polycythemia vera with positive JAK2V617F mutation and myasthenia gravis: A report of two cases
Published 2023“…<p></p><div> <p>Screening for MG in patients with PV positive for JAK2V617F mutation can help in early diagnosis and treatment, resulting in a significant reduction in morbidity and mortality.</p> </div><p></p><h2>Other Information</h2> <p> Published in: Clinical Case Reports<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="http://dx.doi.org/10.1002/ccr3.3574" target="_blank">http://dx.doi.org/10.1002/ccr3.3574</a></p>…”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”