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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems
Published 2021“…</p><h3>Conclusions</h3><p dir="ltr">Our subnational estimates of HIV mortality revealed significant spatial variation and diverging local trends in HIV mortality over time and by age. …”
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Hedonic valuation of land protection methods: implications for cluster development.
Published 2014“…The key findings of the study are: (i) proximity to national or state park land and to city or county open space has a significant positive impact on property values, while proximity to national forest land or to privately conserved land exhibits no significant effects; and, (ii) inclusion of a property within a cluster development decreases its value by 17 to 26 %. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…In this regard, engineering of brighter bioluminescent proteins, i.e. luciferases, has played a significant role. This is acutely exemplified by the engineering of the NLuc <u>luciferase</u>, which is small in size and displays much enhanced bioluminescence and<u> thermal stability</u> compared to previously available luciferases. …”
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Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
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CO, CO2, and SO2 detection based on functionalized graphene nanoribbons: First principles study
Published 2020“…Before modification, the adsorption energies have been found to be −0.260, −0.145, and −0.196 eV due to the adsorption of CO, CO2, and SO2, respectively. After modification, the adsorption energy increased remarkably to −0.538 and −0.767 eV for the cases of AGNR-O-OH-CO2 and AGNR-O-OH-SO2, respectively. …”
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Pt-doped armchair graphene nanoribbon as a promising gas sensor for CO and CO2: DFT study
Published 2020“…After doping, the results revealed a significant increase in the adsorption energy to almost 9 times than the non-doped systems for the cases of CO on Pt–N-AGNR as well as CO2 on both Pt–H-AGNR and Pt–N-AGNR. …”
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SARS-CoV-2 Variants in Lebanon
Published 2024“…Variants of concern (VOC) included Alpha, Beta, Delta, Gamma, and most recently Omicron. Co-infections of SARS-CoV-2 with influenza viruses were detected and led to increased infectivity and SARS-CoV-2 viral load. …”
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Pt-doped armchair graphene nanoribbon as a promising gas sensor for CO and CO<sub>2</sub>: DFT study
Published 2021“…After doping, the results revealed a significant increase in the adsorption energy to almost 9 times than the non-doped systems for the cases of CO on Pt–N-AGNR as well as CO<sub>2</sub> on both Pt–H-AGNR and Pt–N-AGNR. …”
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Suppression of Unstable Flow by Using Rough Surfaces at Small Mass Flow Rates in a Radial Diffuser
Published 2006Get full text
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Methane production enhancement from Tetraselmis biomass co-digestion using frying oil residue as co-substrate and ultrasonication as pretreatment
Published 2023“…Tetraselmis sp. microalgae biomass co-digestion with frying oil residue was investigated without or with an ultrasonication pretreatment to enhance methane production. …”
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CO, CO<sub>2</sub>, and SO<sub>2</sub> detection based on functionalized graphene nanoribbons: First principles study
Published 2020“…After modification, the adsorption energy increased remarkably to −0.538 and −0.767 eV for the cases of AGNR-O-OH-CO<sub>2</sub> and AGNR-O-OH-SO<sub>2</sub>, respectively. …”
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Optimizing the number of players and training bout durations in soccer small‐sided games: Effects on mood balance and technical performance
Published 2025“…Therefore, coaches should consider longer continuous bouts when planning SSGs‐based training to significantly decrease TMD and enhance technical‐tactical performance in soccer SSGs.…”
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ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000]
Published 2021“…Our results first showed a significant increase in HuArgI (Co)-PEG5000 treated cells for both U251 and A172 in autophagosome formation; suggesting activation of autophagy in response to arginine deprivation. …”
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The Effect of HuArgI (Co)-PEG5000 on The Migration of Ovarian Cancer
Published 2020“…It showed that SKOV3 cell line does not show significant invasiveness to collagen. In conclusion, we noticed an effect on ovarian cancer by treating the cells with HuArgI (Co)-PEG5000 which opens the way for further studies on the effect of arginine deprivation and autophagy induction on the migration of ovarian cancer.…”
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masterThesis