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THE SIGNIFICANCE OF MODELING ELECTRODIALYSIS DESALINATION USING MULTI-COMPONENT SALINE WATER
Published 2020Get full text
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Identifying and Assessing the Significance of Digital Twin Enablers in the Construction Industry
Published 2025Get full text
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…<p dir="ltr">Coronavirus Disease of 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has resulted in a massive health crisis across the globe, with some genetic variants gaining enhanced infectivity and competitive fitness, and thus significantly aggravating the global health concern. …”
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Development and Validation of a Class Imbalance-Resilient Cardiac Arrest Prediction Framework Incorporating Multiscale Aggregation, ICA and Explainability
Published 2025“…<p dir="ltr">Objective: Despite advancements in artificial intelligence (AI) for predicting cardiac arrest (CA) with multivariate time-series vital signs data, existing models continue to face significant problems, particularly concerning balance, efficiency, accuracy, and explainability. …”
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Investigation of biomass components on the slow pyrolysis products yield using Aspen Plus for techno-economic analysis
Published 2022“…<p>Prior information on the pyrolysis product behaviour of biomass components-cellulose, hemicellulose and lignin is critical in the selection of feedstock as components have a significant influence on the pyrolysis products yield. …”
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Discourse Analysis of Lexical Cohesive Devices in Shakespearean Sonnets: Exploring their Significant Functions and Roles in ESL Poetry Classes
Published 2024“…Grounded in the interpretivism paradigm, the research utilizes Halliday and Hasan's 1976 model of cohesive devices as an analytical framework. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…<p dir="ltr">Hemodynamically significant patent ductus arteriosus (hsPDA) is a major cause of neonatal morbidity and mortality in extremely low birth weight (ELBW) infants. …”
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Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
Published 2014“…Our data suggest that kefir is able to inhibit the proliferation and induce apoptosis in HT‑29 and Caco‑2 CRC cells, yet it does not exhibit a significant effect on the motility and invasion of these cells in vitro.…”
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Get full text
Get full text
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Mixed precision iterative refinement with adaptive precision sparse approximate inverse preconditioning
Published 2025“…<p dir="ltr">Hardware trends have motivated the development of mixed precision algorithms in numerical linear algebra, which aim to decrease runtime while maintaining acceptable accuracy. …”
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Problematic internet usage: the impact of objectively Recorded and categorized usage time, emotional intelligence components and subjective happiness about usage
Published 2022“…Moreover, gender, age, and happiness with the frequency of phone usage were not significant predictors of PIU. The whole model accounted for the total variance of PIU by 32.5% (Adjusted R<sup>2</sup> = .287). …”
