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Targeting acute myeloid leukemia cells with novel photosensitive ruthenium-based metal-organic compounds. (c2015)
Published 2016“…Of the four final complexes Ru-II3, Ru-II2-III, Ru-II-III2 and Ru-III3, only Ru-II3 and Ru-II2-III have shown significant activity against all tested cell lines in the dark, whereas photo-activation against ML2 has shown a marked increase of potency of all four complexes, even those shown to be biologically inert in the dark, reaching IC50 values in the nM range. …”
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masterThesis -
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Targeting solid tumor cells with novel photosensitive ruthenium-based metal-organic compounds. (c2016)
Published 2016“…This study aims to find the most efficient Ru-based compounds on a set of 6 cell lines from different solid tumors. …”
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masterThesis -
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The Anti-Cancer Effect of Strained Photoactivatable Polypyridyl Ruthenium(II) Complexes on Non-Small-Cell Lung Cancer and Triple Negative Breast Cancer Cells
Published 2020“…Western blot analysis on MDA-MB-231 cells treated with C3 showed a significant increase in BAX/Bcl2 ratio with no significant effect on Pro-caspase-3 expression. …”
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masterThesis -
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The anti-neoplastic activity of novel platinum II and IV complexes against A549 lung cancer cells
Published 2021“…Western blots experiments were also carried out to observe the effect of the drugs on key apoptotic proteins. Data revealed a significant drop in procaspase 3 and a significant increase in Bax/Bcl2 ratio, Cytochrome c, Parp and procaspase 8. …”
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masterThesis -
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Prediction of the Backwater Level Due to Bridge Constriction in Waterways
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doctoralThesis -
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Enhanced catalytic ozonation of ibuprofen using a 3D structured catalyst with MnO<sub>2</sub> nanosheets on carbon microfibers
Published 2021“…The enhanced performance with the new catalyst could be attributed to its significantly increased available surface active sites and improved mass transfer of reaction media, as a result of the special surface and structure properties of this new three-dimensional network-structured catalyst. …”
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Characteristics and health implications of fine particulate matter near urban road site in Islamabad, Pakistan
Published 2024“…The study also identified the presence of semi-volatile organic compounds (SVOCs) in PM2.5 samples, including <u>polycyclic aromatic hydrocarbons</u> (PAHs) and <u>phenolic compounds</u>, with notable variations in their concentrations. …”
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Lead Nitrate Induces Inflammation and Apoptosis in Rat Lungs Through the Activation of NF-κB and AhR Signaling Pathways
Published 2022“…These effects were associated with a significant increase in organic compounds, such as 3-nitrotyrosine and myeloperoxidase, and some inorganic elements, such as selenium. …”
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Solvent Influence on Absorption Spectra and Tautomeric Equilibria of Symmetric Azomethine‐Functionalized Derivatives: Structural Elucidation and Computational Studies
Published 2023“…The impact of solvent polarity on absorption spectra were investigated via solvatochromic shifts. For instance, compound <b>3 c</b> displayed a gradual shift of the maximum absorption to the red area when the solvent polarity was increased, recording a 21 nm of bathochromic shift. …”
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Arsenic: A double-edged sword
Published 2014“…Long-term exposure significantly increases the risk of heart disease, diabetes, and makes numerous different cell types turn cancerous. …”
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Gold-Conjugated Curcumin as a Novel Therapeutic Agent against Brain-Eating Amoebae
Published 2020“…Moreover, these compounds were also conjugated with gold nanoparticles to further increase their amoebicidal activities. …”
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Exploring the dynamics of algae-associated microbiome during the scale-up process of Tetraselmis sp. microalgae: A metagenomics approach
Published 2023“…Microbial profiling of each successive stage revealed lower abundance of eukaryotic organisms, whereas bacterial abundance increased notably resulting in a significant decrease in Tetraselmis sp. abundance. …”
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Exploring the dynamics of algae-associated microbiome during the scale-up process of Tetraselmis sp. microalgae: A metagenomics approach
Published 2024“…Microbial profiling of each successive stage revealed lower abundance of eukaryotic organisms, whereas bacterial abundance increased notably resulting in a significant decrease in Tetraselmis sp. abundance. …”
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Formation of Trihalomethanes during Seawater Chlorination
Published 2010“…Chlorination of seawater has shown significant increase in total THMs (TTHMs) and in bromoform concentrations. …”
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The effect of graphene structural integrity on the power factor of tin selenide nanocomposite
Published 2021“…The increased power factor is attributed to the homogeneous distribution of graphene, which results in a significant increase in electrical conductivity. …”