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Showing 1 - 20 results of 55 for search '(( significant dangers based ) OR ( significant ((genes decrease) OR (greatest decrease)) ))', query time: 0.11s Refine Results
  1. 1
    The rising danger of heat waves

    The rising danger of heat waves by Nature Research (16552612)

    Published 2015
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  2. 2
    A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity

    A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

    Published 2024
    “…<p dir="ltr">NanoLuc (NLuc) <u>luciferase</u> has found extensive application in designing a range of <u>biologica</u><u>l</u><u> assays,</u> including <u>gene expression analysis</u>, protein-protein interaction, and protein conformational changes due to its enhanced brightness and small size. …”
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  3. 3
    Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells

    Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

    Published 2019
    “…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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  4. 4
    Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion

    Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion by Khoury, Nathalie

    Published 2014
    “…The expression of certain genes involved in proliferation and apoptosis was measured using reverse transcriptase‑polymerase chain reaction (RT‑PCR) and western blotting. …”
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  5. 5
    Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk

    Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk by Merhi, Mahmoud

    Published 2015
    “…Moreover, a significant smoking-gene interaction is determined with CYP1A1 MspI polymorphism rs4646903 and is associated with a decreased risk of CAD in current smokers (OR 0.52137). …”
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  6. 6
    Analysis of Diabetes Apps to Assess Privacy-Related Permissions: Systematic Search of Apps

    Analysis of Diabetes Apps to Assess Privacy-Related Permissions: Systematic Search of Apps by José Javier Flors-Sidro (18518946)

    Published 2021
    “…</p><h3>Results</h3><p dir="ltr">Approximately 60% of the analyzed diabetes apps requested potentially dangerous permissions, which pose a significant risk to users’ data privacy. …”
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  7. 7
    Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications

    Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications by Jingxuan Shan (4711089)

    Published 2019
    “…We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …”
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  8. 8
    Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients

    Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients by Esraa K. Al-Amleh (16023071)

    Published 2022
    “…Platelet counts, on the other hand, dramatically decreased in both IM and (HU + IM).</p><h3>Conclusion</h3><p dir="ltr">Because the studied genes (BCL2, PP2A, CIP2A, and WT1) are participating in cell proliferation and death, the findings show that the examined genes are significant to understand the efficacy of various therapies. …”
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  9. 9
    Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes

    Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes by Maryam Aghadi (17128819)

    Published 2022
    “…Lack of FOXA2 resulted in significant alterations in the expression of key developmental and functional genes in hepatic progenitors (HP) and mature hepatocytes (MH) as well as an increase in the expression of ER stress markers. …”
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  10. 10
    Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4

    Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 by Olfa Khalifa (10914452)

    Published 2023
    “…</p> <p>Results: Treatment with 200nM Ex-4 for 3h decreased the OA-induced lipid buildup significantly (p<0.05). …”
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  11. 11
    Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss

    Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss by Meritxell Espino Guarch (18810097)

    Published 2018
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  12. 12
    Forecasting model to predict project success based on the contractors’ characteristics

    Forecasting model to predict project success based on the contractors’ characteristics by AlSuwaidi, Khalid Waleed Rashid Deemas

    Published 2018
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  13. 13
    A New Genetic-Based Tabu Search Algorithm For Unit Commitment Problem

    A New Genetic-Based Tabu Search Algorithm For Unit Commitment Problem by Mantawy, A. H.

    Published 2020
    “…This paper presents a new algorithm based on integrating the use of genetic algorithms and tabu search methods to solve the unit commitment problem. …”
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  14. 14
    Security Supply Chain Using UAVs: Validation and Development of a UAV-Based Model for Qatar’s Mega Sporting Events

    Security Supply Chain Using UAVs: Validation and Development of a UAV-Based Model for Qatar’s Mega Sporting Events by Khalifa AL-Dosari (17931434)

    Published 2023
    “…The key findings of the study are: (1) a valid and reliable UAV-based cybersecurity framework for FIFA mega sporting events was developed; (2) five critical factors were identified, including traceability, security and privacy, trust, acceptability, and preparedness; (3) all factors were significantly and positively correlated, highlighting the complexity of managing security systems in mega sporting events.…”
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  15. 15
    BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells

    BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells by Ali Alhoshani (3720718)

    Published 2020
    “…This effect was associated with a significant increase in the percentage of apoptotic MDA-MB-231 cells and in the expression of the apoptotic genes, caspase 3, caspase 7, and BAX, with inhibition of antiapoptotic gene, BCL-2 levels. …”
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  16. 16
    Aqueous urtica dioica leaves extract inhibits proliferation of acute myeloid leukemia cells in vitro

    Aqueous urtica dioica leaves extract inhibits proliferation of acute myeloid leukemia cells in vitro by Rizk, Sandra

    Published 2017
    “…The decrease was more significant after 72hr with an IC50 at 16mg/ml. …”
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  17. 17
    Investigating vulnerability for developing eating disorders in a multi-confessional population

    Investigating vulnerability for developing eating disorders in a multi-confessional population by Doumit, Rita

    Published 2016
    “…Affiliating as Christian was found to significantly decrease the vulnerability to developing an ED. …”
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  18. 18
    Proteome analysis of Candida albicans cell wall mutants. (c2011)

    Proteome analysis of Candida albicans cell wall mutants. (c2011) by Koussa, Joseph Wissam

    Published 2011
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    masterThesis
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  19. 19
    Optimizing the Cleaning Frequency of Solar Photovoltaic (PV) systems Using Numerical Analysis

    Optimizing the Cleaning Frequency of Solar Photovoltaic (PV) systems Using Numerical Analysis by Kaiss, El-Cheikh Amer Kais

    Published 2021
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  20. 20
    Investigating vulnerability for developing eating disorders in a multi-confessional lebanese sample

    Investigating vulnerability for developing eating disorders in a multi-confessional lebanese sample by Khazen, Georges

    Published 2015
    “…Being Christian was found to significantly decrease the vulnerability to developing an ED. …”
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    conferenceObject
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