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Showing 1 - 20 results of 418 for search '(( significant decrease (increase OR increased) ) OR ( significant event decrease ))', query time: 0.12s Refine Results
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    A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

    Published 2024
    “…This is specifically relevant in designing assays that require bioluminescence for extended periods, such as in the case of biosensors designed for monitoring slow enzymatic or <u>cellular signaling</u> reactions, without necessitating multiple rounds of luciferase substrate addition or any specialized reagents that result in increased assay costs. In the current manuscript, we report a mutant NLuc that possesses a stable and prolonged bioluminescence activity, albeit lower than the wild-type NLuc, and envisage a wider application of the mutant NLuc in designing biosensors for monitoring slower biological and biomedical events.…”
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    The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... by Wesal Habbab (17346961)

    Published 2019
    “…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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    Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells by Shebaby, Wassim N.

    Published 2014
    “…The increase in apoptosis in response to treatment was also apparent in the increase in BAX and the decrease in Bcl-2 levels as well as the proteolytic cleavage of both caspase-3 and PARP as revealed by Western blot. …”
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    The Impact of a Computerized Potassium Alert on Adverse Drug Events and Pharmacists' Interventions by Mansour, Hanine

    Published 2010
    “…Conclusions: Implementation of a computerized pharmacy alert resulted in a statistically significant decrease in adverse drug events related to hyperkalemia in our institution. …”
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    Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex by Wesam S. Ahmed (10170053)

    Published 2022
    “…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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    Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion by Khoury, Nathalie

    Published 2014
    “…Western blotting results revealed an upregulation in Bax:Bcl‑2 ratio, confirming the pro‑apoptotic effect of kefir, and an increase in p53 independent‑p21 expression upon kefir treatment. …”
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    Examining time-to-transport decisions in Emergency Medical Services by Hassan Farhat (9000509)

    Published 2024
    “…The Schoenfeld plot (Figure 2) demonstrates that multiple variables have a significant impact on increasing the time-to-handover.…”
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    Masked phenomenon: renal and cardiovascular complications; review and updates by Elmukhtar Habas (14777677)

    Published 2024
    “…The masked phenomenon (MP) (MHTN and MUHTN) increases susceptibility to end-organ damage (a two-fold greater risk for cardiovascular events and kidney dysfunction). …”
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    Oral contraceptive pills and possible adverse effects by Stone, Rebecca H

    Published 2014
    “…The major adverse effect associated with COCs is an increased risk of a cardiovascular event. COCs are contraindicated for women with increased cardiovascular risk, increased thromboembolic risk, significant liver disease, systemic lupus erythematosus, or migraine with aura. …”
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    OSRA Grant Cycle 5 Public Reports : Project Title: Coping with prenatal bereavement and perceived stress in current pregnancy: correlates to parental perception of the child and bo... by Pia Tohme Khalaf (17425551)

    Published 2023
    “…<p dir="ltr">This study reveals a significant connection between prenatal bonding or attachment during pregnancy and various factors such as maternal age, anxiety, and stress, including those attributed to specific events like the COVID-19 pandemic. …”
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    β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo by Daaboul, Hamid E.

    Published 2017
    “…A significant decrease in protein levels of p53 and Bcl-2 and a significant increase in p21 and Bax were observed. …”
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    Sleeping habits during COVID-19 induced confinement: A study from Jordan by Mahmoud A. Alomari (14780446)

    Published 2021
    “…Participants (n = 1846) were recruited in the study, of which >92% reported a variety of confinement procedures such as self-quarantine, physical distancing, banning of public events, school closure, and lockdown. Majority of the participants (53–59%) reported an increase in most of the sleep parameters except a decrease (49.1%) in daytime sleep. …”
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    The effect of Ramadan focused education on patients with type 2 diabetes: A systematic review and meta-analysis by Hoda Gad (6470522)

    Published 2020
    “…Pre-Ramadan education was associated with a significant reduction in HbA1c (SMD −0.46, 95% CI −0.65 to −0.27P < 0.05) and LDL (SMD −0.09, 95% CI −0.13 to −0.04P < 0.05), an increase in TG (SMD 0.07, 95% CI −0.23 to 0.93P < 0.05) and weight (SMD 0.44, 95% CI 0.06 to 0.81P < 0.05) and no change in hypoglycemic events, BMI, TC, HDL or blood pressure (P > 0.05) during Ramadan.…”
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    Effect of Hydroxycut Intake on Fasted and Postprandial Lipemia in Rats by Daher, Costantine F.

    Published 2015
    “…A significant increase in serum blood glucose level was observed with hydroxycut intake in the presence of a high-fat diet. …”
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