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Defining Quality in Early Childhood Care and Education in Lebanon
Published 2020“…The question is “how is quality defined by the Ministry of Public Health (MoPH) and other stakeholders as seen through the licensing requirements for childcare centres in Lebanon. …”
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A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity
Published 2024“…However, questions related to its mechanism of interaction with the substrate, furimazine, as well as bioluminescence activity remain elusive. Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …”
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Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells
Published 2019“…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
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Performance evaluation of 3D-printed PLA composites doped with WE43 magnesium alloy for bone tissue engineering applications
Published 2025“…While a low Mg content (5 %) only slightly impacted the print quality and dimensions, higher Mg concentrations (10 % and 15 %) led to increased weight, rougher surfaces, dimensional shrinkage in height, and overall poorer formation quality. Adding WE43 alloy to PLA decreased the average pore sizes of the composites. …”
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Natural resource dependence and war nexus: new insights
Published 2025“…However, we notice that this probability is decreasing in the level of economic development and democratization, and with the size of the services sector and trade openness. …”
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Indomethacin as a Rescue Therapy for Patent Ductus Arteriosus in Extremely Premature Infants after Failed Ibuprofen Treatment
Published 2023“…While most PDAs close after one 3-day course of either medicine, a repeat course may be necessary before considering surgical ligation for those who remain with hsPDAs. In our practice, we administer one or two courses of ibuprofen followed by a single course of indomethacin if the PDA has not shown closure or decrease in size on the echocardiogram (echo) exam. …”
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The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu...
Published 2019“…Somewhat surprisingly, the catalytically active form, methylated PP2A (mePP2A) was significantly decreased. In close correlation to these data, the phosphorylation state of two substrate proteins, sensitive to PP2A activity, GSK3β and Tau were found to be increased. …”
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A FeedForward–Convolutional Neural Network to Detect Low-Rate DoS in IoT
Published 2022“…The Canadian Institute of Cybersecurity Denial of Service 2017 (CIC DoS 2017) dataset is used for the study. An iterative wrapper-based feature selection using Support Vector Machine (SVM) is used to derive the significant features required for detection. …”
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When Should a Brain MRI Be Performed in Children with New-Onset Seizures? Results of a Large Prospective Trial
Published 2021“…The presence of developmental delay and seizure type at presentation remained significant in a multivariate analysis. CONCLUSIONS: We documented a relatively high rate of epileptogenic lesions in children with new-onset seizures, with the presence of developmental delay and specific seizure types being associated with a higher likelihood of detecting an epileptogenic lesion on neuroimaging. …”
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Fourier-Transform Infrared Imaging Spectroscopy and Laser Ablation -ICPMS New Vistas for Biochemical Analyses of Ischemic Stroke in Rat Brain
Published 2018“…</p><p dir="ltr"><br></p><h3>Results</h3><p dir="ltr">The FTIR results revealed that in the lesioned gray matter the relative distribution of lipid, lipid acyl and protein contents decreased significantly. Also at this locus, there was a significant increase in aggregated protein as detected by high-levels Aβ1-42. …”
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BIM for Economic Green Retrofitting based on LEED- EBOM
Published 2020“…The current situation of global warming requires many actions to reduce the GHG emissions and resources depletion so the governments around the world defined several visions and plans to be achieved within long term and short-term programs. …”
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Assessing the Impact of Reactive Power Droop on Inverter Based Microgrid Stability
Published 2021“…Further, the domain of stability chart can serve as a useful tool for defining the micro-grid droop gain operational boundaries and for assessing and comparing inverter-based micro-grid control schemes.…”
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Research Based Pedagogy to Enhance Quality of Learning: A Study Among Selected Higher Education Institutions in the UAE
Published 2024“…Research Based Pedagogy is referred to as a significant concept that would facilitate in creating research culture and to graduate students with high cognitive thinking order. …”
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