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Showing 1 - 20 results of 106 for search '(( significant degree increased ) OR ( significant genes decrease ))', query time: 0.09s Refine Results
  1. 1

    Evaluating the degree of difficulty of laparoscopic colorectal surgery by Dimassi, Hani

    Published 2008
    “…These concerns have now been addressed in randomized controlled trials that have shown that the laparoscopic approach is associated with the same significant short-term benefits without a compromise in oncological long-term outcomes.7- 10 It is therefore anticipated that there will be an increased demand for laparoscopic colorectal procedures in the future, with many surgeons entering this field. …”
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  2. 2

    Proteomic Characterization Of Clinical Candida glabrata Isolates With Varying Degrees Of Virulence And Resistance To Fluconazole by Zeidan, Ahmad

    Published 2024
    “…Candida glabrata, an opportunistic fungal pathogen, is a significant contributor to mortality among individuals with weakened immune systems. …”
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    masterThesis
  3. 3

    The Role of Project Management Soft Skills in Increasing Project Success by AL AWABDEH, JOYCE YOUSEF

    Published 2017
    “…As the world economy shifts towards an increasingly globalised market, the degree of competition becomes a more significant challenge which organisations face. …”
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  4. 4

    A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

    Published 2024
    “…<p dir="ltr">NanoLuc (NLuc) <u>luciferase</u> has found extensive application in designing a range of <u>biologica</u><u>l</u><u> assays,</u> including <u>gene expression analysis</u>, protein-protein interaction, and protein conformational changes due to its enhanced brightness and small size. …”
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    Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

    Published 2019
    “…Among the tested molecules, LY411575, a potent γ-secretase and Notch signaling inhibitor, exhibited significant inhibitory effects on osteoblastic differentiation of hBMSCs manifested by reduced ALP activity, mineralized matrix formation, and decreased osteoblast-specific gene expression as well as in vivo ectopic bone formation. …”
  7. 7

    Kefir exhibits anti‑proliferative and pro‑apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion by Khoury, Nathalie

    Published 2014
    “…The expression of certain genes involved in proliferation and apoptosis was measured using reverse transcriptase‑polymerase chain reaction (RT‑PCR) and western blotting. …”
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  8. 8

    Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk by Merhi, Mahmoud

    Published 2015
    “…Moreover, a significant smoking-gene interaction is determined with CYP1A1 MspI polymorphism rs4646903 and is associated with a decreased risk of CAD in current smokers (OR 0.52137). …”
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  9. 9

    Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications by Jingxuan Shan (4711089)

    Published 2019
    “…We found a highly significant association between the <b><i>CCND1</i></b><b> </b><b>rs614367-TT</b> genotype (OR = 5.14; <i>P</i> = 0.004) and TNBC risk, and identified a significant association between the <b>rs614367-T</b> allele and decreased PFS in TNBC. …”
  10. 10

    Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients by Esraa K. Al-Amleh (16023071)

    Published 2022
    “…Platelet counts, on the other hand, dramatically decreased in both IM and (HU + IM).</p><h3>Conclusion</h3><p dir="ltr">Because the studied genes (BCL2, PP2A, CIP2A, and WT1) are participating in cell proliferation and death, the findings show that the examined genes are significant to understand the efficacy of various therapies. …”
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    Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes by Maryam Aghadi (17128819)

    Published 2022
    “…Lack of FOXA2 resulted in significant alterations in the expression of key developmental and functional genes in hepatic progenitors (HP) and mature hepatocytes (MH) as well as an increase in the expression of ER stress markers. …”
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    Long non-coding RNA MALAT1 promotes steatosis in HepG2 cells by modulating target gene expression in presence of Exendin-4 by Olfa Khalifa (10914452)

    Published 2023
    “…</p> <p>Results: Treatment with 200nM Ex-4 for 3h decreased the OA-induced lipid buildup significantly (p<0.05). …”
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    BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells by Ali Alhoshani (3720718)

    Published 2020
    “…This effect was associated with a significant increase in the percentage of apoptotic MDA-MB-231 cells and in the expression of the apoptotic genes, caspase 3, caspase 7, and BAX, with inhibition of antiapoptotic gene, BCL-2 levels. …”
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    Diabetes mellitus and renal failure by Aoun, S.

    Published 2001
    “…Independent of the degree of renal failure, a fall in the glomerular filtration rate was also associated with increased aortic PWV. …”
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  19. 19

    Spatial and temporal assessment of metal pollution in the sediments of the Qaraoun reservoir, Lebanon by Wazne, Mahmoud

    Published 2016
    “…Total metal concentrations and the environmental indices indicated increased pollution with time. Total organic carbon data showed a remarkable and significant increase in the organic fraction in 2013 relative to previous years. …”
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  20. 20

    Elemental distributions in the marine sediments off Doha, Qatar: role of urbanisation and coastal dynamics by Varis Mohammed Hasna (22046888)

    Published 2024
    “…The Geoaccumulation Index resulted in a slight pollution of Cd, while other elements are unpolluted. The Degree of Contamination reveals low degree of contamination of sediments, and the Pollution Load Index illustrates no significant pollution in the sediments off Doha.…”